Effect of medetomidine-butorphanol and dexmedetomidine-butorphanol combinations on intraocular pressure in healthy dogs

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F12%3A43871417" target="_blank" >RIV/62157124:16170/12:43871417 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1111/j.1467-2995.2011.00703.x" target="_blank" >http://dx.doi.org/10.1111/j.1467-2995.2011.00703.x</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/j.1467-2995.2011.00703.x" target="_blank" >10.1111/j.1467-2995.2011.00703.x</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Effect of medetomidine-butorphanol and dexmedetomidine-butorphanol combinations on intraocular pressure in healthy dogs

Popis výsledku v původním jazyce

Objective To assess the effects of intravenous (IV) medetomidine-butorphanol and IV dexmedetomidine-butorphanol on intraocular pressure (IOP). Study design Prospective, randomized, blinded clinical study. Animals Forty healthy dogs. Mean +/- SD body mass37.6 +/- 6.6 kg and age 1.9 +/- 1.3 years. Methods Dogs were allocated randomly to receive an IV combination of dexmedetomidine, 0.3 mg m-2, combined with butorphanol, 6 mg m-2, (group DEX) or medetomidine 0.3 mg m-2, combined with butorphanol 6 mg m-2,(group MED). IOP and pulse (PR) and respiratory (fR) rates were measured prior to (baseline) and at 10 (T10), 20 (T20), 30 (T30) and 40 (T40) minutes after drug administration. Oxygen saturation of hemoglobin (SpO2) was monitored following sedation. Data were analyzed by anova followed by Dunnetts tests for multiple comparisons. Changes were considered significant when p { 0.05. Results Following drug administration, PR and fR were decreased significantly at all time points but did not

Název v anglickém jazyce

Effect of medetomidine-butorphanol and dexmedetomidine-butorphanol combinations on intraocular pressure in healthy dogs

Popis výsledku anglicky

Objective To assess the effects of intravenous (IV) medetomidine-butorphanol and IV dexmedetomidine-butorphanol on intraocular pressure (IOP). Study design Prospective, randomized, blinded clinical study. Animals Forty healthy dogs. Mean +/- SD body mass37.6 +/- 6.6 kg and age 1.9 +/- 1.3 years. Methods Dogs were allocated randomly to receive an IV combination of dexmedetomidine, 0.3 mg m-2, combined with butorphanol, 6 mg m-2, (group DEX) or medetomidine 0.3 mg m-2, combined with butorphanol 6 mg m-2,(group MED). IOP and pulse (PR) and respiratory (fR) rates were measured prior to (baseline) and at 10 (T10), 20 (T20), 30 (T30) and 40 (T40) minutes after drug administration. Oxygen saturation of hemoglobin (SpO2) was monitored following sedation. Data were analyzed by anova followed by Dunnetts tests for multiple comparisons. Changes were considered significant when p { 0.05. Results Following drug administration, PR and fR were decreased significantly at all time points but did not

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinary anaesthesia and analgesia

ISSN

1467-2987

e-ISSN

—

Svazek periodika

39

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

301-305

Kód UT WoS článku

000303158700011

EID výsledku v databázi Scopus

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