Tissue factor, plasminogen and plasminogen activator inhibitor in dogs with gastric dilatation and volvulus.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F14%3A43873283" target="_blank" >RIV/62157124:16170/14:43873283 - isvavai.cz</a>

Výsledek na webu

—

DOI - Digital Object Identifier

—

Jazyk výsledku

angličtina

Název v původním jazyce

Tissue factor, plasminogen and plasminogen activator inhibitor in dogs with gastric dilatation and volvulus.

Popis výsledku v původním jazyce

Gastric dilatation and volvulus syndrome (GDV) is frequently associated with alteration in coagulation and fibrinolytic system leading to disseminated intravascular coagulation (DIC). However, trigger of DIC in these dogs is not known yet. Aim of this study was to compare level of tissue factor (TF), plasminogen (P) and plasminogen activator inhibitor (PAI) in dogs with GDV and healthy controls and to correlate severity of haemostatic imbalance with these parameters. Platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT), level of fibrinogen (FBG) and D-dimers, TF, P and PAI were measured in 19 dogs with GDV and 12 healthy dogs. In dogs with GDV, alteration of each PLT, PT, aPTT, FBG and D-dimers was scored by 1 point. Levels of TF, P and PAI were compared between GDV and control dogs using Mann-Whitney U test, correlation of score and TF, P and PAI was performed using Spearman correlation coefficient. Significant difference between control dogs and d

Název v anglickém jazyce

Tissue factor, plasminogen and plasminogen activator inhibitor in dogs with gastric dilatation and volvulus.

Popis výsledku anglicky

Gastric dilatation and volvulus syndrome (GDV) is frequently associated with alteration in coagulation and fibrinolytic system leading to disseminated intravascular coagulation (DIC). However, trigger of DIC in these dogs is not known yet. Aim of this study was to compare level of tissue factor (TF), plasminogen (P) and plasminogen activator inhibitor (PAI) in dogs with GDV and healthy controls and to correlate severity of haemostatic imbalance with these parameters. Platelet count (PLT), prothrombin time (PT), activated partial thromboplastin time (aPTT), level of fibrinogen (FBG) and D-dimers, TF, P and PAI were measured in 19 dogs with GDV and 12 healthy dogs. In dogs with GDV, alteration of each PLT, PT, aPTT, FBG and D-dimers was scored by 1 point. Levels of TF, P and PAI were compared between GDV and control dogs using Mann-Whitney U test, correlation of score and TF, P and PAI was performed using Spearman correlation coefficient. Significant difference between control dogs and d

Druh

O - Ostatní výsledky

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

—

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů