Cystatins of the parasitic Nematodes - Trichinella spiralis, T. britovi and T. pseudospiralis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F14%3A43873316" target="_blank" >RIV/62157124:16170/14:43873316 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Cystatins of the parasitic Nematodes - Trichinella spiralis, T. britovi and T. pseudospiralis

Popis výsledku v původním jazyce

The nematodes of the genus Trichinella are intracellular parasites which invade the cells of small intestine and skeletal muscles. They infect a broad range of worldwide distributed hosts, like mammals, birds and reptiles. All Trichinella spp. are zoonotic; six of twelve genotypes have been detected in humans. The serious human disease is called trichinellosis and it has been documented in 55 countries. Our work is focused on cystatins - a reversible inhibitors of cystein peptidases of three trichinellaspecies - Trichinella spiralis, T. britovi and T. pseudospiralis. Cystatins are compounds of excretory-secretory products (ESP) which are released by muscle larvae (L1) into the external environment. They are involved in many essential biological processes like growth, development, digestion and migration and also in manipulation of the host immunne system by parasite. Up to now, the specific primers were designed for "multi cystatin-like domain" gene of T. spiralis, T. britovi and T. p

Název v anglickém jazyce

Cystatins of the parasitic Nematodes - Trichinella spiralis, T. britovi and T. pseudospiralis

Popis výsledku anglicky

The nematodes of the genus Trichinella are intracellular parasites which invade the cells of small intestine and skeletal muscles. They infect a broad range of worldwide distributed hosts, like mammals, birds and reptiles. All Trichinella spp. are zoonotic; six of twelve genotypes have been detected in humans. The serious human disease is called trichinellosis and it has been documented in 55 countries. Our work is focused on cystatins - a reversible inhibitors of cystein peptidases of three trichinellaspecies - Trichinella spiralis, T. britovi and T. pseudospiralis. Cystatins are compounds of excretory-secretory products (ESP) which are released by muscle larvae (L1) into the external environment. They are involved in many essential biological processes like growth, development, digestion and migration and also in manipulation of the host immunne system by parasite. Up to now, the specific primers were designed for "multi cystatin-like domain" gene of T. spiralis, T. britovi and T. p

Druh

O - Ostatní výsledky

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů