Impact of stress on the gut microbiome of free-ranging western lowland gorillas

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876283" target="_blank" >RIV/62157124:16170/18:43876283 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60077344:_____/18:00498843 RIV/68081766:_____/18:00489276 RIV/62157124:16810/18:43876283

Výsledek na webu

<a href="http://dx.doi.org/10.1099/mic.0.000587" target="_blank" >http://dx.doi.org/10.1099/mic.0.000587</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1099/mic.0.000587" target="_blank" >10.1099/mic.0.000587</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Impact of stress on the gut microbiome of free-ranging western lowland gorillas

Popis výsledku v původním jazyce

Exposure to stressors can negatively impact the mammalian gastrointestinal microbiome (GIM). Here, we used 454 pyrosequencing of 16S rRNA bacterial gene amplicons to evaluate the impact of physiological stress, as evidenced by faecal glucocorticoid metabolites (FGCM; ng/g), on the GIM composition of free-ranging western lowland gorillas (Gorilla gorilla gorilla). Although we found no relationship between GIM alpha diversity (H) and FGCM levels, we observed a significant relationship between the relative abundances of particular bacterial taxa and FGCM levels. Specifically, members of the family Anaerolineaceae (rho=0.4, FDR q=0.01), genus Clostridium cluster XIVb (rho=0.35, FDR q=0.02) and genus Oscillibacter (rho=0.35, FDR q=0.02) were positively correlated with FGCM levels. Thus, while exposure to stressors appears to be associated with minor changes in the gorilla GIM, the consequences of these changes are unknown. Our results may have implications for conservation biology as well as for our overall understanding of factors influencing the non-human primate GIM.

Název v anglickém jazyce

Impact of stress on the gut microbiome of free-ranging western lowland gorillas

Popis výsledku anglicky

Exposure to stressors can negatively impact the mammalian gastrointestinal microbiome (GIM). Here, we used 454 pyrosequencing of 16S rRNA bacterial gene amplicons to evaluate the impact of physiological stress, as evidenced by faecal glucocorticoid metabolites (FGCM; ng/g), on the GIM composition of free-ranging western lowland gorillas (Gorilla gorilla gorilla). Although we found no relationship between GIM alpha diversity (H) and FGCM levels, we observed a significant relationship between the relative abundances of particular bacterial taxa and FGCM levels. Specifically, members of the family Anaerolineaceae (rho=0.4, FDR q=0.01), genus Clostridium cluster XIVb (rho=0.35, FDR q=0.02) and genus Oscillibacter (rho=0.35, FDR q=0.02) were positively correlated with FGCM levels. Thus, while exposure to stressors appears to be associated with minor changes in the gorilla GIM, the consequences of these changes are unknown. Our results may have implications for conservation biology as well as for our overall understanding of factors influencing the non-human primate GIM.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Microbiology-SGM

ISSN

1350-0872

e-ISSN

—

Svazek periodika

164

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

5

Strana od-do

40-44

Kód UT WoS článku

000429491800005

EID výsledku v databázi Scopus

2-s2.0-85039900477