Newborn foal with atypical myopathy.
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F18%3A43876643" target="_blank" >RIV/62157124:16170/18:43876643 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1111/jvim.15236" target="_blank" >http://dx.doi.org/10.1111/jvim.15236</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jvim.15236" target="_blank" >10.1111/jvim.15236</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Newborn foal with atypical myopathy.
Popis výsledku v původním jazyce
The case of atypical myopathy (AM) in newborn Haflinger foal with clinical signs of depression and weakness appearing 6 hours after birth resulting in recumbency 12 hours after birth is described. The foal?s dam was diagnosed with AM in the 6th month of gestation based on clinical signs of a myopathy, elevated serum activity of creatine kinase, metabolomic analysis and the presence of methylenecyclopropyl acetyl carnitine (MCPA-carnitine) in the blood. At the time of delivery, the mare was grazing on a pasture near sycamore trees but was free of clinical signs of AM. Metabolomic analysis of the foal?s blood revealed increased concentrations of acylcarnitines and MCPA-carnitine consistent with metabolic profiles of blood from AM affected horses. Two theories could explain this observation (a) hypoglycin A or its metabolites accumulated in the mare?s placenta with consequent transfer to fetus or (b) these compounds were secreted into mare?s milk.
Název v anglickém jazyce
Newborn foal with atypical myopathy.
Popis výsledku anglicky
The case of atypical myopathy (AM) in newborn Haflinger foal with clinical signs of depression and weakness appearing 6 hours after birth resulting in recumbency 12 hours after birth is described. The foal?s dam was diagnosed with AM in the 6th month of gestation based on clinical signs of a myopathy, elevated serum activity of creatine kinase, metabolomic analysis and the presence of methylenecyclopropyl acetyl carnitine (MCPA-carnitine) in the blood. At the time of delivery, the mare was grazing on a pasture near sycamore trees but was free of clinical signs of AM. Metabolomic analysis of the foal?s blood revealed increased concentrations of acylcarnitines and MCPA-carnitine consistent with metabolic profiles of blood from AM affected horses. Two theories could explain this observation (a) hypoglycin A or its metabolites accumulated in the mare?s placenta with consequent transfer to fetus or (b) these compounds were secreted into mare?s milk.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
40301 - Veterinary science
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Journal of Veterinary Internal Medicine
ISSN
0891-6640
e-ISSN
—
Svazek periodika
32
Číslo periodika v rámci svazku
5
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
5
Strana od-do
1768-1772
Kód UT WoS článku
000447414300034
EID výsledku v databázi Scopus
2-s2.0-85053623609