Anesthesia with intramuscular administration of alfaxalone in Spanish ribbed newt (Pleurodeles waltl)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F20%3A43878691" target="_blank" >RIV/62157124:16170/20:43878691 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S1557506320300045" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1557506320300045</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1053/j.jepm.2020.01.003" target="_blank" >10.1053/j.jepm.2020.01.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Anesthesia with intramuscular administration of alfaxalone in Spanish ribbed newt (Pleurodeles waltl)

Popis výsledku v původním jazyce

The objective of this investigation was to assess the usefulness of three different doses of alfaxalone administered intramuscularly in amphibian species. Thirty-two healthy, adult (5-9 years old) captive Spanish ribbed newts (Pleurodeles wait!) were used. Alfaxalone at a dose of 15, 20, and 30 mg/kg was administered into the muscles of the front legs of each newt, with a 4-week washout period between trials. Heart rate and depth of sedation were assessed for each animal prior to the administration of anesthetic (T-0), and at 2-minute intervals over the initial 20 minutes, then at 5-minute intervals over 60 minutes, and at 15-minute intervals until a full duration of 120 minutes for each trial. The average induction time was reduced with increasing doses. The recovery period was prolonged with increasing doses. Intramuscular administration of alfaxalone proved a feasible method for immobilization and sedation in Spanish ribbed newts and resulted in loss of both the escape reflex and righting reflex.

Název v anglickém jazyce

Anesthesia with intramuscular administration of alfaxalone in Spanish ribbed newt (Pleurodeles waltl)

Popis výsledku anglicky

The objective of this investigation was to assess the usefulness of three different doses of alfaxalone administered intramuscularly in amphibian species. Thirty-two healthy, adult (5-9 years old) captive Spanish ribbed newts (Pleurodeles wait!) were used. Alfaxalone at a dose of 15, 20, and 30 mg/kg was administered into the muscles of the front legs of each newt, with a 4-week washout period between trials. Heart rate and depth of sedation were assessed for each animal prior to the administration of anesthetic (T-0), and at 2-minute intervals over the initial 20 minutes, then at 5-minute intervals over 60 minutes, and at 15-minute intervals until a full duration of 120 minutes for each trial. The average induction time was reduced with increasing doses. The recovery period was prolonged with increasing doses. Intramuscular administration of alfaxalone proved a feasible method for immobilization and sedation in Spanish ribbed newts and resulted in loss of both the escape reflex and righting reflex.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Exotic Pet Medicine

ISSN

1557-5063

e-ISSN

—

Svazek periodika

33

Číslo periodika v rámci svazku

APR

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

4

Strana od-do

23-26

Kód UT WoS článku

000528623000006

EID výsledku v databázi Scopus

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