Electrolyte, Oestradiol and Progesterone Concentrations in Ovarian Cyst Fluid in Guinea Pigs (Cavia porcellus)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F22%3A43880158" target="_blank" >RIV/62157124:16170/22:43880158 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0021997522000032" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0021997522000032</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.jcpa.2022.01.003" target="_blank" >10.1016/j.jcpa.2022.01.003</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Electrolyte, Oestradiol and Progesterone Concentrations in Ovarian Cyst Fluid in Guinea Pigs (Cavia porcellus)

Popis výsledku v původním jazyce

Despite their high prevalence, the aetiopathogenesis of ovarian cysts in guinea pigs (Cavia porcellus) is unknown. We examined tissue samples of cystic ovaries from 20 guinea pigs by histopathology and immunohistochemistry for CD10 antigen, and determined the concentrations of Na+, K+, Cl- oestradiol and progesterone in the cyst fluid. Cystic rete ovarii were found in all 20 guinea pigs but no follicular cysts. Concentrations of Na+ (142.2 +/- 5.04 mmol/l), K+ (5.6 +/- 0.76 mmol/l) and Cl- (116.1 +/- 5.25 mmol/l) corresponded to extracellular, rather than intracellular, fluid indicating that rete ovarii cysts in guinea pigs are transudative in nature. A positive correlation was found between Na+ and Cl- concentrations (r =0.7713, P &lt; 0.0001). The mean concentrations of oestradiol (61.9 +/- 17.44 pg/ml) and progesterone (2.7 +/- 5.42 ng/ml) in the cyst fluid were higher than expected because the rete epithelium is not known to have steroidogenic activity. A negative correlation was found between oestradiol and progesterone concentrations in cyst fluid (r = -0.4296, P =0.0178). Possible pathogenetic mechanisms of cystic rete ovarii in guinea pigs are discussed.(c) 2022 Elsevier Ltd. All rights reserved.

Název v anglickém jazyce

Electrolyte, Oestradiol and Progesterone Concentrations in Ovarian Cyst Fluid in Guinea Pigs (Cavia porcellus)

Popis výsledku anglicky

Despite their high prevalence, the aetiopathogenesis of ovarian cysts in guinea pigs (Cavia porcellus) is unknown. We examined tissue samples of cystic ovaries from 20 guinea pigs by histopathology and immunohistochemistry for CD10 antigen, and determined the concentrations of Na+, K+, Cl- oestradiol and progesterone in the cyst fluid. Cystic rete ovarii were found in all 20 guinea pigs but no follicular cysts. Concentrations of Na+ (142.2 +/- 5.04 mmol/l), K+ (5.6 +/- 0.76 mmol/l) and Cl- (116.1 +/- 5.25 mmol/l) corresponded to extracellular, rather than intracellular, fluid indicating that rete ovarii cysts in guinea pigs are transudative in nature. A positive correlation was found between Na+ and Cl- concentrations (r =0.7713, P &lt; 0.0001). The mean concentrations of oestradiol (61.9 +/- 17.44 pg/ml) and progesterone (2.7 +/- 5.42 ng/ml) in the cyst fluid were higher than expected because the rete epithelium is not known to have steroidogenic activity. A negative correlation was found between oestradiol and progesterone concentrations in cyst fluid (r = -0.4296, P =0.0178). Possible pathogenetic mechanisms of cystic rete ovarii in guinea pigs are discussed.(c) 2022 Elsevier Ltd. All rights reserved.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of comparative pathology

ISSN

0021-9975

e-ISSN

1532-3129

Svazek periodika

192

Číslo periodika v rámci svazku

April 2022

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

7

Strana od-do

11-17

Kód UT WoS článku

000790872500002

EID výsledku v databázi Scopus

2-s2.0-85124741287