Prevalence and histopathological classification of equine melanocytic tumours in the Czech Republic and Slovakia

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F24%3A43881176" target="_blank" >RIV/62157124:16170/24:43881176 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16270/24:43881176

Výsledek na webu

<a href="https://doi.org/10.2754/avb202493030269" target="_blank" >https://doi.org/10.2754/avb202493030269</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2754/avb202493030269" target="_blank" >10.2754/avb202493030269</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Prevalence and histopathological classification of equine melanocytic tumours in the Czech Republic and Slovakia

Popis výsledku v původním jazyce

Equine melanocytic tumours are of great concern for horse owners, especially those who own grey horses. These tumours can be initially benign but data from literature suggest that all equine melanocytic tumours have a potential to undergo a malignant transformation and even develop distant metastases. This study aimed to diagnose and classify equine melanocytic tumours, assess their prevalence in relation to the horse&apos;s coat colour, sex, and age, and evaluate their occurrence sites. Over the period of four years (2020-2023), biopsies and necropsies of 203 horses were performed; melanocytic tumours were diagnosed in 34 cases (16.75%). Based on the morphological features of the neoplastic cells and presence of distant metastases, 3 horses (8.82%) were diagnosed with early-stage melanocytic lesions, 10 (29.41%) with melanocytomas, 4 (11.76%) with low-grade melanoma, 8 (23.53%) with intermediate-grade melanoma, 6 (17.65%) with metastatic melanoma and 3 (8.82%) with high-grade anaplastic melanoma. There was a significantly higher prevalence of the most malignant types of melanocytic tumours (metastatic melanoma, high-grade anaplastic melanoma) in horses over the age of 15 years (70%, P &lt; 0.05).

Název v anglickém jazyce

Prevalence and histopathological classification of equine melanocytic tumours in the Czech Republic and Slovakia

Popis výsledku anglicky

Equine melanocytic tumours are of great concern for horse owners, especially those who own grey horses. These tumours can be initially benign but data from literature suggest that all equine melanocytic tumours have a potential to undergo a malignant transformation and even develop distant metastases. This study aimed to diagnose and classify equine melanocytic tumours, assess their prevalence in relation to the horse&apos;s coat colour, sex, and age, and evaluate their occurrence sites. Over the period of four years (2020-2023), biopsies and necropsies of 203 horses were performed; melanocytic tumours were diagnosed in 34 cases (16.75%). Based on the morphological features of the neoplastic cells and presence of distant metastases, 3 horses (8.82%) were diagnosed with early-stage melanocytic lesions, 10 (29.41%) with melanocytomas, 4 (11.76%) with low-grade melanoma, 8 (23.53%) with intermediate-grade melanoma, 6 (17.65%) with metastatic melanoma and 3 (8.82%) with high-grade anaplastic melanoma. There was a significantly higher prevalence of the most malignant types of melanocytic tumours (metastatic melanoma, high-grade anaplastic melanoma) in horses over the age of 15 years (70%, P &lt; 0.05).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

40301 - Veterinary science

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta veterinaria Brno

ISSN

0001-7213

e-ISSN

1801-7576

Svazek periodika

93

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

269-274

Kód UT WoS článku

001338130400002

EID výsledku v databázi Scopus

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