Piezoelektrický biosensor pro jednoduchou serologickou diagnostiku tularemie u infikovaných zajíců polních (Lepus europaeus)

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F07%3A00001339" target="_blank" >RIV/62157124:16270/07:00001339 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60162694:G44__/07:00001757

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Piezoelectric biosensor for a simple serological diagnosis of tularemia in infected European brown hares (Lepus europaeus)

Popis výsledku v původním jazyce

Piezoelectric biosensor was used for diagnosis of infection by Francisella tularensis subsp. holarctica in European brown hares. Two kinds of experiments were performed in this study. First, sera from experimentally infected European brown hares (Lepus europaeus) were assayed by piezoelectric biosensor and the seventh day post infection was found as the first one when statistically significant diagnosis of tularemia was possible; all other sera collected from hares later than on day 7 following the infection were found tularemia positive. Typing to classify the field strain of F. tularensis used for the experimental infection was confirmed by proteome study. Second, sera from 35 European brown hare specimens sampled at hunting grounds and tested as tularemia positive by slow agglutination allowed diagnosis of tularemia by the piezoelectric biosensor. All these sera of naturally infected hares were found as tularemia positive, too. Efficacy of the piezoelectric biosensor for the serolog

Název v anglickém jazyce

Piezoelectric biosensor for a simple serological diagnosis of tularemia in infected European brown hares (Lepus europaeus)

Popis výsledku anglicky

Piezoelectric biosensor was used for diagnosis of infection by Francisella tularensis subsp. holarctica in European brown hares. Two kinds of experiments were performed in this study. First, sera from experimentally infected European brown hares (Lepus europaeus) were assayed by piezoelectric biosensor and the seventh day post infection was found as the first one when statistically significant diagnosis of tularemia was possible; all other sera collected from hares later than on day 7 following the infection were found tularemia positive. Typing to classify the field strain of F. tularensis used for the experimental infection was confirmed by proteome study. Second, sera from 35 European brown hare specimens sampled at hunting grounds and tested as tularemia positive by slow agglutination allowed diagnosis of tularemia by the piezoelectric biosensor. All these sera of naturally infected hares were found as tularemia positive, too. Efficacy of the piezoelectric biosensor for the serolog

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

<a href="/cs/project/OPUOFVZ200602" target="_blank" >OPUOFVZ200602: BOJAGENS - Faktory virulence intracelulárního patogena Francisella tularensis zařazeného do kategorie A bojových biologických agens</a><br>

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Sensors

ISSN

1424-8220

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

10

Strana od-do

2825-2834

Kód UT WoS článku

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EID výsledku v databázi Scopus

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