Risk of single and combined exposure of birds to non-steroidal anti-inflammatory drugs and lead

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F12%3A43871479" target="_blank" >RIV/62157124:16270/12:43871479 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60162694:G44__/12:43874639

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Risk of single and combined exposure of birds to non-steroidal anti-inflammatory drugs and lead

Popis výsledku v původním jazyce

Pharmaceuticals and heavy metals have been identified as environmental contaminants toxic to birds and posing serious threats to declining populations of raptors worldwide. The aim of the present study was to test the hypothesis that a sublethal combination of NSAIDs and lead induces more pronounced effects than single exposures in birds. A total of 40 Japanese quails at the age of 2 months and average weight of 180g were on a random basis divided into four experimental groups of 10 specimens. Six leadshots in the total weight of 1.5 grams were inserted into the crop on day 0 of the experiment, while a total of 5 mg/kg of diclofenac administered intramuscularly were divided into treatments on days 0 and 5. Group responses were compared using haematology and biochemistry after 10 days. There was no mortality in control and both single and combined diclofenac and lead exposure groups, nor did the birds show any clinical signs of intoxication. Univariate analyses of blood parameters yiel

Název v anglickém jazyce

Risk of single and combined exposure of birds to non-steroidal anti-inflammatory drugs and lead

Popis výsledku anglicky

Pharmaceuticals and heavy metals have been identified as environmental contaminants toxic to birds and posing serious threats to declining populations of raptors worldwide. The aim of the present study was to test the hypothesis that a sublethal combination of NSAIDs and lead induces more pronounced effects than single exposures in birds. A total of 40 Japanese quails at the age of 2 months and average weight of 180g were on a random basis divided into four experimental groups of 10 specimens. Six leadshots in the total weight of 1.5 grams were inserted into the crop on day 0 of the experiment, while a total of 5 mg/kg of diclofenac administered intramuscularly were divided into treatments on days 0 and 5. Group responses were compared using haematology and biochemistry after 10 days. There was no mortality in control and both single and combined diclofenac and lead exposure groups, nor did the birds show any clinical signs of intoxication. Univariate analyses of blood parameters yiel

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Svazek periodika

33

Číslo periodika v rámci svazku

suppl. 3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

145-150

Kód UT WoS článku

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EID výsledku v databázi Scopus

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