Fish embryos as alternative models in toxicology: A review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F15%3A43873808" target="_blank" >RIV/62157124:16270/15:43873808 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Fish embryos as alternative models in toxicology: A review

Popis výsledku v původním jazyce

Our environment is confronted with growing number of xenobiotics. These bioactive compounds can reach the aquatic environment in many ways and have considerable effects on aquatic biota. The fish acute toxicity test in a mandatory step in chemicals toxicity testing. However, its ecotoxicological relevance is questionable. Moreover, fish are subjected to considerable pain and suffering. In accordance with reduction, refinement and replacement philosophy, fish embryos are considered as replacement or refinement method since these developmental stages are not legislatively protected (Directive 2010/63/EU) and are likely to experience less pain or suffering. The aim of this review was to summarize available data on fish embryo toxicity tests and introducetheir possible perspectives in modern toxicology. Based on the conducted studies, the fish embryo toxicity test is a reasonable alternative to fish acute toxicity test. Its range of possible application is impressive with many future pers

Název v anglickém jazyce

Fish embryos as alternative models in toxicology: A review

Popis výsledku anglicky

Our environment is confronted with growing number of xenobiotics. These bioactive compounds can reach the aquatic environment in many ways and have considerable effects on aquatic biota. The fish acute toxicity test in a mandatory step in chemicals toxicity testing. However, its ecotoxicological relevance is questionable. Moreover, fish are subjected to considerable pain and suffering. In accordance with reduction, refinement and replacement philosophy, fish embryos are considered as replacement or refinement method since these developmental stages are not legislatively protected (Directive 2010/63/EU) and are likely to experience less pain or suffering. The aim of this review was to summarize available data on fish embryo toxicity tests and introducetheir possible perspectives in modern toxicology. Based on the conducted studies, the fish embryo toxicity test is a reasonable alternative to fish acute toxicity test. Its range of possible application is impressive with many future pers

Druh

D - Stať ve sborníku

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Ochrana zvířat a welfare 2015

ISBN

978-80-7305-759-6

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

136-139

Název nakladatele

Veterinární a farmaceutická univerzita Brno

Místo vydání

Brno

Místo konání akce

Brno

Datum konání akce

8. 10. 2015

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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