Different IncI1 plasmids from Escherichia coli carry ISEcp1-bla(CTX-M-15) associated with different Tn2-derived elements

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F15%3A43873837" target="_blank" >RIV/62157124:16270/15:43873837 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/62157124:16810/15:43873837

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.plasmid.2015.04.007" target="_blank" >http://dx.doi.org/10.1016/j.plasmid.2015.04.007</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.plasmid.2015.04.007" target="_blank" >10.1016/j.plasmid.2015.04.007</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Different IncI1 plasmids from Escherichia coli carry ISEcp1-bla(CTX-M-15) associated with different Tn2-derived elements

Popis výsledku v původním jazyce

The bla(CTX-M-15) gene, encoding the globally dominant CTX-M-15 extended-spectrum beta-lactamase, has generally been found in a 2.971-kb ISEcp1-bla(CTX-M-15)-orf477 Delta transposition unit, with ISEcp1 providing a promoter. In available IncF plasmid sequences from Escherichia coli, this transposition unit interrupts a truncated copy of transposon Tn2 that lies within larger multiresistance regions. In E. coli, bla(CTX-M-15) is also commonly associated with IncI1 plasmids and here three such plasmids from E. coli clinical isolates from western Sydney 2006-2007 have been sequenced. The plasmid backbones are organised similarly to those of other IncI1 plasmids, but have insertions and/or deletions and sequence differences. Each plasmid also has a different insertion carrying bla(CTX-M-15). pJIE113 (IncI1 sequence type ST31) is almost identical to plasmids isolated from the 2011 E. coli 0104:H4 outbreak in Europe, where the typical bla(CTX-M-15) transposition unit interrupts a complete Tn

Název v anglickém jazyce

Different IncI1 plasmids from Escherichia coli carry ISEcp1-bla(CTX-M-15) associated with different Tn2-derived elements

Popis výsledku anglicky

The bla(CTX-M-15) gene, encoding the globally dominant CTX-M-15 extended-spectrum beta-lactamase, has generally been found in a 2.971-kb ISEcp1-bla(CTX-M-15)-orf477 Delta transposition unit, with ISEcp1 providing a promoter. In available IncF plasmid sequences from Escherichia coli, this transposition unit interrupts a truncated copy of transposon Tn2 that lies within larger multiresistance regions. In E. coli, bla(CTX-M-15) is also commonly associated with IncI1 plasmids and here three such plasmids from E. coli clinical isolates from western Sydney 2006-2007 have been sequenced. The plasmid backbones are organised similarly to those of other IncI1 plasmids, but have insertions and/or deletions and sequence differences. Each plasmid also has a different insertion carrying bla(CTX-M-15). pJIE113 (IncI1 sequence type ST31) is almost identical to plasmids isolated from the 2011 E. coli 0104:H4 outbreak in Europe, where the typical bla(CTX-M-15) transposition unit interrupts a complete Tn

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EB - Genetika a molekulární biologie

OECD FORD obor

—

Projekt

—

Návaznosti

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Plasmid

ISSN

0147-619X

e-ISSN

—

Svazek periodika

80

Číslo periodika v rámci svazku

SI

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

118-126

Kód UT WoS článku

000359511900013

EID výsledku v databázi Scopus

—