Cross-correlation analysis of the Desulfovibrio growth parameters of intestinal species isolated from people with colitis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F18%3A43876467" target="_blank" >RIV/62157124:16270/18:43876467 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/18:00103673 RIV/62157124:16370/18:43876467

Výsledek na webu

<a href="http://dx.doi.org/10.2478/s11756-018-0118-2" target="_blank" >http://dx.doi.org/10.2478/s11756-018-0118-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/s11756-018-0118-2" target="_blank" >10.2478/s11756-018-0118-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cross-correlation analysis of the Desulfovibrio growth parameters of intestinal species isolated from people with colitis

Popis výsledku v původním jazyce

Sulfate-reducing bacteria can be involved in inflammatory bowel disease. Cross-correlation parameters of their metabolic process in the gut have never been reported before. The aim of the research was to statistically (cross-correlation) evaluate the parameters of growth (biomass) of Desulfovibrio species from colitis people and healthy as well as to investigate the change in dissimilatory sulfate reduction of these bacterial strains. The microbiological, biochemical, chemical, and statistical methods were used in the research. The cross-correlation analysis indicates that the strains isolated from people with colitis shifted to the right side of Y axe by biomass accumulation, sulfate consumption, lactate oxidation as well as hydrogen sulfide and acetate production, compared with the strains isolated from healthy individuals. Different percentages were observed in shifting to the right side of Y axe: biomass accumulation 26%, sulfate consumption 1.5%, sulfide production 5%, lactate oxidation 3% and acetate production 12%. The biomass accumulation of intestinal sulfate-reducing bacteria and their hydrogen sulfide production are the main factors in inflammatory bowel disease development, including ulcerative colitis. Acetate production showed lesser influence while sulfate consumption and lactate oxidation are negligible factors in the inflammatory bowel disease.

Název v anglickém jazyce

Cross-correlation analysis of the Desulfovibrio growth parameters of intestinal species isolated from people with colitis

Popis výsledku anglicky

Sulfate-reducing bacteria can be involved in inflammatory bowel disease. Cross-correlation parameters of their metabolic process in the gut have never been reported before. The aim of the research was to statistically (cross-correlation) evaluate the parameters of growth (biomass) of Desulfovibrio species from colitis people and healthy as well as to investigate the change in dissimilatory sulfate reduction of these bacterial strains. The microbiological, biochemical, chemical, and statistical methods were used in the research. The cross-correlation analysis indicates that the strains isolated from people with colitis shifted to the right side of Y axe by biomass accumulation, sulfate consumption, lactate oxidation as well as hydrogen sulfide and acetate production, compared with the strains isolated from healthy individuals. Different percentages were observed in shifting to the right side of Y axe: biomass accumulation 26%, sulfate consumption 1.5%, sulfide production 5%, lactate oxidation 3% and acetate production 12%. The biomass accumulation of intestinal sulfate-reducing bacteria and their hydrogen sulfide production are the main factors in inflammatory bowel disease development, including ulcerative colitis. Acetate production showed lesser influence while sulfate consumption and lactate oxidation are negligible factors in the inflammatory bowel disease.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30304 - Public and environmental health

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biologia

ISSN

0006-3088

e-ISSN

—

Svazek periodika

73

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

7

Strana od-do

1137-1143

Kód UT WoS článku

000448724700011

EID výsledku v databázi Scopus

2-s2.0-85054150965