Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16270%2F18%3A43877014" target="_blank" >RIV/62157124:16270/18:43877014 - isvavai.cz</a>
Výsledek na webu
<a href="http://dx.doi.org/10.1016/j.scitotenv.2018.03.076" target="_blank" >http://dx.doi.org/10.1016/j.scitotenv.2018.03.076</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.scitotenv.2018.03.076" target="_blank" >10.1016/j.scitotenv.2018.03.076</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review
Popis výsledku v původním jazyce
After application, antidepressants, like other pharmaceuticals, are excreted from human body in their native form or as metabolites and enter the aquatic environment via different pathways. As concentrations of antidepressant residues in water continue to increase, their effects on non-target animals are being discussed. The aim of this study is to summarize current knowledge about the effects of wateborne antidepressants on non-target animals living in surface waters - invertebrates, fish and amphibians. Selective serotonin reuptake inhibitors such as fluoxetine, sertraline, and citalopram have been found to effect behavior, reproduction, and development in both invertebrates and vertebrates. Venlafaxine, belonging to the group of selective serotonin-noradrenalin reuptake inhibitors, not only affected behavior but also showed the potential to reduce survival in fish. Tricylic antidepressants are known to have various side-effectswhen consumed by humans. Moreover, in fish, exposure resulted in a significant increase in mortality, developmental retardation, morphological anomalies, and pathological changes in brain, heart, and cranial and caudal kidney. In addition, changes in antioxidant enzyme activity as well as increased lipid peroxidation were observed, even at the lowest tested concentrations. According to current knowledge, antidepressants occuring in surface water are able to affect the behavior, reproduction, development, and survival of aquatic invertebrates and vertebrates. (C) 2018 Elsevier B.V. All rights reserved.
Název v anglickém jazyce
Effects of waterborne antidepressants on non-target animals living in the aquatic environment: A review
Popis výsledku anglicky
After application, antidepressants, like other pharmaceuticals, are excreted from human body in their native form or as metabolites and enter the aquatic environment via different pathways. As concentrations of antidepressant residues in water continue to increase, their effects on non-target animals are being discussed. The aim of this study is to summarize current knowledge about the effects of wateborne antidepressants on non-target animals living in surface waters - invertebrates, fish and amphibians. Selective serotonin reuptake inhibitors such as fluoxetine, sertraline, and citalopram have been found to effect behavior, reproduction, and development in both invertebrates and vertebrates. Venlafaxine, belonging to the group of selective serotonin-noradrenalin reuptake inhibitors, not only affected behavior but also showed the potential to reduce survival in fish. Tricylic antidepressants are known to have various side-effectswhen consumed by humans. Moreover, in fish, exposure resulted in a significant increase in mortality, developmental retardation, morphological anomalies, and pathological changes in brain, heart, and cranial and caudal kidney. In addition, changes in antioxidant enzyme activity as well as increased lipid peroxidation were observed, even at the lowest tested concentrations. According to current knowledge, antidepressants occuring in surface water are able to affect the behavior, reproduction, development, and survival of aquatic invertebrates and vertebrates. (C) 2018 Elsevier B.V. All rights reserved.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
40301 - Veterinary science
Návaznosti výsledku
Projekt
—
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2018
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Science of the Total Environment
ISSN
0048-9697
e-ISSN
—
Svazek periodika
631-632
Číslo periodika v rámci svazku
August
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
6
Strana od-do
789-794
Kód UT WoS článku
000432471900080
EID výsledku v databázi Scopus
2-s2.0-85043535722