Adipocyte fatty acid binding protein v bělošské populaci: nový marker metabolického syndromu?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F06%3A00000705" target="_blank" >RIV/62157124:16370/06:00000705 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Adipocyte fatty acid binding protein in a Caucasian population: a new marker of metabolic syndrome?

Popis výsledku v původním jazyce

Background: Adipocyte fatty acid binding protein (A-FABP) has been suggested as playing an important role in the pathogenesis of metabolic syndrome. The aim of this study was to evaluate serum A-FABP as a marker of metabolic syndrome and to assess its predictive accuracy in a Caucasian population. Materials and methods: Anthropometric and serum analyses were performed for body mass index (BMI), waist circumference, A-FABP, insulin, triglycerides, total cholesterol, high-density lipoprotein-cholesterol (HDL-c), low-density lipoprotein-cholesterol (LDL-c), uric acid, and glucose on 67 non-obese, healthy subjects and 71 subjects with metabolic syndrome. Quicki-quantitative insulin sensitivity check index, receiver operating characteristic curve (ROC-curve) and &#967;2 analysis were completed. Results:Compared with healthy controls, subjects with metabolic syndrome had a significantly higher A-FABP serum level (mean: 42,4 vs. 23,7?g L&#8722;1;P< 0,01). The AFABP serum level correlated with

Název v anglickém jazyce

Adipocyte fatty acid binding protein in a Caucasian population: a new marker of metabolic syndrome?

Popis výsledku anglicky

Background: Adipocyte fatty acid binding protein (A-FABP) has been suggested as playing an important role in the pathogenesis of metabolic syndrome. The aim of this study was to evaluate serum A-FABP as a marker of metabolic syndrome and to assess its predictive accuracy in a Caucasian population. Materials and methods: Anthropometric and serum analyses were performed for body mass index (BMI), waist circumference, A-FABP, insulin, triglycerides, total cholesterol, high-density lipoprotein-cholesterol (HDL-c), low-density lipoprotein-cholesterol (LDL-c), uric acid, and glucose on 67 non-obese, healthy subjects and 71 subjects with metabolic syndrome. Quicki-quantitative insulin sensitivity check index, receiver operating characteristic curve (ROC-curve) and &#967;2 analysis were completed. Results:Compared with healthy controls, subjects with metabolic syndrome had a significantly higher A-FABP serum level (mean: 42,4 vs. 23,7?g L&#8722;1;P< 0,01). The AFABP serum level correlated with

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

European Journal of Clinical Investigation

ISSN

0014-2972

e-ISSN

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Svazek periodika

36

Číslo periodika v rámci svazku

N

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

5

Strana od-do

621-625

Kód UT WoS článku

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EID výsledku v databázi Scopus

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