5-Fluorouracil- Characteristics and Analytical Determination

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F11%3A43870808" target="_blank" >RIV/62157124:16370/11:43870808 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.2174/157341211794708767" target="_blank" >http://dx.doi.org/10.2174/157341211794708767</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/157341211794708767" target="_blank" >10.2174/157341211794708767</a>

Jazyk výsledku

angličtina

Název v původním jazyce

5-Fluorouracil- Characteristics and Analytical Determination

Popis výsledku v původním jazyce

5-fluorouracil (5-FU or f5U) is a pyrimidine analogue, and is used as an antineoplastic drug. Working with antineoplastic drugs constitutes a health hazard for the people who handle them, mainly because of their mutagenicity, teratogenicity and carcinogenicity. This is the reason, why the determination of antineoplastic drugs in wipe samples obtained from the hospital departments, where antineoplastic drugs are prepared or administered is growing in importance. 5-fluorouracil has some unusual pharmacological characteristics, which make it suitable for therapeutic drug monitoring. Thus, its determination in plasma and other body fluids or in urine is important, too. Like other drugs, 5-fluorouracil is also determined in formulations during quality control or stability studies.

Název v anglickém jazyce

5-Fluorouracil- Characteristics and Analytical Determination

Popis výsledku anglicky

5-fluorouracil (5-FU or f5U) is a pyrimidine analogue, and is used as an antineoplastic drug. Working with antineoplastic drugs constitutes a health hazard for the people who handle them, mainly because of their mutagenicity, teratogenicity and carcinogenicity. This is the reason, why the determination of antineoplastic drugs in wipe samples obtained from the hospital departments, where antineoplastic drugs are prepared or administered is growing in importance. 5-fluorouracil has some unusual pharmacological characteristics, which make it suitable for therapeutic drug monitoring. Thus, its determination in plasma and other body fluids or in urine is important, too. Like other drugs, 5-fluorouracil is also determined in formulations during quality control or stability studies.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Pharmaceutical Analysis

ISSN

1573-4129

e-ISSN

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Svazek periodika

7

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

1-11

Kód UT WoS článku

000287799600001

EID výsledku v databázi Scopus

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