Self-assembly of extremely uniform polymeric nanoparticles prepared by microfluidic mixing

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F18%3A43876924" target="_blank" >RIV/62157124:16370/18:43876924 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Self-assembly of extremely uniform polymeric nanoparticles prepared by microfluidic mixing

Popis výsledku v původním jazyce

Purpose of the study was to prepare highly monodisperse polymeric nanoparticles which could be used as a model to study the effect of particles size to oral mucosa penetration capabilities in sublingual vaccination formulations. Herein model poly lactic-co-glycolic acid (PLGA) nanoparticles were prepared by nanoprecipitation by microfluidic mixing platform NanoAssemblr. The quality of prepared nanoparticles was more than sufficient to use them for further study within our new mucoadhesive nanofibre-based sublingual vaccination patch system. Hence it can be assumed that microfluidics will become an indispensable tool for further development on the field of nanomedicine in the future.

Název v anglickém jazyce

Self-assembly of extremely uniform polymeric nanoparticles prepared by microfluidic mixing

Popis výsledku anglicky

Purpose of the study was to prepare highly monodisperse polymeric nanoparticles which could be used as a model to study the effect of particles size to oral mucosa penetration capabilities in sublingual vaccination formulations. Herein model poly lactic-co-glycolic acid (PLGA) nanoparticles were prepared by nanoprecipitation by microfluidic mixing platform NanoAssemblr. The quality of prepared nanoparticles was more than sufficient to use them for further study within our new mucoadhesive nanofibre-based sublingual vaccination patch system. Hence it can be assumed that microfluidics will become an indispensable tool for further development on the field of nanomedicine in the future.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů