Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F17%3A50005585" target="_blank" >RIV/62690094:18450/17:50005585 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.dovepress.com/onset-of-mortality-increase-with-age-and-age-trajectories-of-mortality-peer-reviewed-article-CIA" target="_blank" >https://www.dovepress.com/onset-of-mortality-increase-with-age-and-age-trajectories-of-mortality-peer-reviewed-article-CIA</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2147/CIA.S119327" target="_blank" >10.2147/CIA.S119327</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries

Popis výsledku v původním jazyce

Background: The answer to the question &quot;At what age does aging begin?&quot; is tightly related to the question &quot;Where is the onset of mortality increase with age?&quot; Age affects mortality rates from all diseases differently than it affects mortality rates from nonbiological causes. Mortality increase with age in adult populations has been modeled by many authors, and little attention has been given to mortality decrease with age after birth. Materials and methods: Nonbiological causes are excluded, and the category &quot;all diseases&quot; is studied. It is analyzed in Denmark, Finland, Norway, and Sweden during the period 1994-2011, and all possible models are screened. Age trajectories of mortality are analyzed separately: before the age category where mortality reaches its minimal value and after the age category. Results: Resulting age trajectories from all diseases showed a strong minimum, which was hidden in total mortality. The inverse proportion between mortality and age fitted in 54 of 58 cases before mortality minimum. The Gompertz model with two parameters fitted as mortality increased with age in 17 of 58 cases after mortality minimum, and the Gompertz model with a small positive quadratic term fitted data in the remaining 41 cases. The mean age where mortality reached minimal value was 8 (95% confidence interval 7.05-8.95) years. The figures depict an age where the human population has a minimal risk of death from biological causes. Conclusion: Inverse proportion and the Gompertz model fitted data on both sides of the mortality minimum, and three parameters determined the shape of the age-mortality trajectory. Life expectancy should be determined by the two standard Gompertz parameters and also by the single parameter in the model c/x. All-disease mortality represents an alternative tool to study the impact of age. All results are based on published data.

Název v anglickém jazyce

Onset of mortality increase with age and age trajectories of mortality from all diseases in the four Nordic countries

Popis výsledku anglicky

Background: The answer to the question &quot;At what age does aging begin?&quot; is tightly related to the question &quot;Where is the onset of mortality increase with age?&quot; Age affects mortality rates from all diseases differently than it affects mortality rates from nonbiological causes. Mortality increase with age in adult populations has been modeled by many authors, and little attention has been given to mortality decrease with age after birth. Materials and methods: Nonbiological causes are excluded, and the category &quot;all diseases&quot; is studied. It is analyzed in Denmark, Finland, Norway, and Sweden during the period 1994-2011, and all possible models are screened. Age trajectories of mortality are analyzed separately: before the age category where mortality reaches its minimal value and after the age category. Results: Resulting age trajectories from all diseases showed a strong minimum, which was hidden in total mortality. The inverse proportion between mortality and age fitted in 54 of 58 cases before mortality minimum. The Gompertz model with two parameters fitted as mortality increased with age in 17 of 58 cases after mortality minimum, and the Gompertz model with a small positive quadratic term fitted data in the remaining 41 cases. The mean age where mortality reached minimal value was 8 (95% confidence interval 7.05-8.95) years. The figures depict an age where the human population has a minimal risk of death from biological causes. Conclusion: Inverse proportion and the Gompertz model fitted data on both sides of the mortality minimum, and three parameters determined the shape of the age-mortality trajectory. Life expectancy should be determined by the two standard Gompertz parameters and also by the single parameter in the model c/x. All-disease mortality represents an alternative tool to study the impact of age. All results are based on published data.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10101 - Pure mathematics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical interventions in aging

ISSN

1178-1998

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NZ - Nový Zéland

Počet stran výsledku

13

Strana od-do

161-173

Kód UT WoS článku

000392326100001

EID výsledku v databázi Scopus

—