The role of PR 10 proteins and molecular components of moulds and yeast in atopic dermatitis patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F22%3A50019517" target="_blank" >RIV/62690094:18450/22:50019517 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11150/22:10449449 RIV/00179906:_____/22:10449449

Výsledek na webu

<a href="https://doi.org/10.1080/09540105.2022.2130183" target="_blank" >https://doi.org/10.1080/09540105.2022.2130183</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/09540105.2022.2130183" target="_blank" >10.1080/09540105.2022.2130183</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The role of PR 10 proteins and molecular components of moulds and yeast in atopic dermatitis patients

Popis výsledku v původním jazyce

This study aims to analyse the results of specific IgE to molecular components of PR 10 proteins, mould and yeast in atopic dermatitis (AD) patients,to find significant sets of molecular components in pairs and triplets in the relation to the severity of atopic dermatitis and the occurrence of asthma bronchiale and allergic rhinitis.The examination of the sensitization to molecular components with ALEX2 Allergy Explorer testing was performed. The level of specific IgE was recorded with jittered box plots,the Kruskal–Wallis test was used to compare the levels of specific IgE in different forms of AD. The relation between the results of specific IgE was evaluated withCoefficient of correlation (Kendall tau-b). The comparison of significant rules was performed with Fisher–Freeman–Halton exact test and with tests on proportions.Altogether 100 atopic dermatitis patients were examined. Molecular components Fra a 1 + 3, Mal d 1, Api g 1, Mala s 11 and Asp f 6 are recorded as a single molecularcomponent with relation to the severe form of AD; these components are associated in pairs and triplets with molecular components Cor a 1.0401, Cor a 1.0103, Fag s 1, Alt a 1and with the occurrence of allergic rhinitis. Results are presented in static and interactive tables and plots.

Název v anglickém jazyce

The role of PR 10 proteins and molecular components of moulds and yeast in atopic dermatitis patients

Popis výsledku anglicky

This study aims to analyse the results of specific IgE to molecular components of PR 10 proteins, mould and yeast in atopic dermatitis (AD) patients,to find significant sets of molecular components in pairs and triplets in the relation to the severity of atopic dermatitis and the occurrence of asthma bronchiale and allergic rhinitis.The examination of the sensitization to molecular components with ALEX2 Allergy Explorer testing was performed. The level of specific IgE was recorded with jittered box plots,the Kruskal–Wallis test was used to compare the levels of specific IgE in different forms of AD. The relation between the results of specific IgE was evaluated withCoefficient of correlation (Kendall tau-b). The comparison of significant rules was performed with Fisher–Freeman–Halton exact test and with tests on proportions.Altogether 100 atopic dermatitis patients were examined. Molecular components Fra a 1 + 3, Mal d 1, Api g 1, Mala s 11 and Asp f 6 are recorded as a single molecularcomponent with relation to the severe form of AD; these components are associated in pairs and triplets with molecular components Cor a 1.0401, Cor a 1.0103, Fag s 1, Alt a 1and with the occurrence of allergic rhinitis. Results are presented in static and interactive tables and plots.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30502 - Other medical science

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Food and Agricultural Immunology

ISSN

0954-0105

e-ISSN

1465-3443

Svazek periodika

33

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

19

Strana od-do

780-798

Kód UT WoS článku

000870506400001

EID výsledku v databázi Scopus

2-s2.0-85140364701