Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F21%3A50018171" target="_blank" >RIV/62690094:18470/21:50018171 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/75010330:_____/21:00013468

Výsledek na webu

<a href="https://www.mdpi.com/2072-6651/13/6/399" target="_blank" >https://www.mdpi.com/2072-6651/13/6/399</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/toxins13060399" target="_blank" >10.3390/toxins13060399</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Popis výsledku v původním jazyce

In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults died by hitherto unknown turkey &quot;X&quot; disease in England. The disease was associated with Brazilian groundnut meal affected by Aspergillus flavus. The toxin was named Aspergillus flavus toxin-aflatoxin. From the point of view of agriculture, aflatoxins show the utmost importance. Until now, a total of 20 aflatoxins have been described, with B-1, B-2, G(1), and G(2) aflatoxins being the most significant. Contamination by aflatoxins is a global health problem. Aflatoxins pose acutely toxic, teratogenic, immunosuppressive, carcinogenic, and teratogenic effects. Besides food insecurity and human health, aflatoxins affect humanity at different levels, such as social, economical, and political. Great emphasis is placed on aflatoxin mitigation using biocontrol methods. Thus, this review is focused on aflatoxins in terms of historical development, the principal milestones of aflatoxin research, and recent data on their toxicity and different ways of mitigation.

Název v anglickém jazyce

Aflatoxins: History, Significant Milestones, Recent Data on Their Toxicity and Ways to Mitigation

Popis výsledku anglicky

In the early 1960s the discovery of aflatoxins began when a total of 100,000 turkey poults died by hitherto unknown turkey &quot;X&quot; disease in England. The disease was associated with Brazilian groundnut meal affected by Aspergillus flavus. The toxin was named Aspergillus flavus toxin-aflatoxin. From the point of view of agriculture, aflatoxins show the utmost importance. Until now, a total of 20 aflatoxins have been described, with B-1, B-2, G(1), and G(2) aflatoxins being the most significant. Contamination by aflatoxins is a global health problem. Aflatoxins pose acutely toxic, teratogenic, immunosuppressive, carcinogenic, and teratogenic effects. Besides food insecurity and human health, aflatoxins affect humanity at different levels, such as social, economical, and political. Great emphasis is placed on aflatoxin mitigation using biocontrol methods. Thus, this review is focused on aflatoxins in terms of historical development, the principal milestones of aflatoxin research, and recent data on their toxicity and different ways of mitigation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10620 - Other biological topics

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Toxins

ISSN

2072-6651

e-ISSN

—

Svazek periodika

13

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

23

Strana od-do

"Article Number399"

Kód UT WoS článku

000666708000001

EID výsledku v databázi Scopus

2-s2.0-85108205503