Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F11%3A%230001313" target="_blank" >RIV/65269705:_____/11:#0001313 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/11:00065759

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males

Popis výsledku v původním jazyce

A high pulse pressure (PP) is a marker of increased artery stiffness and represents a well - established independent predictor for cardiovascular morbidity and mortality. The objective of the research was to determine whether invasively measured centralaortic PP was related to the presence and severity of coronary artery disease. In total 1075 consecutive stable male patients undergoing diagnostic coronary angiography with a preserved left ventricular function were included. Diseased coronary vessel (DCV) was defined by the presence of &gt; 50% stenosis. Results: Men were divided into 3 groups according to the increased value of PP. The average PP in the tertils was 47.8+-7.1 vs. 67.0+-4.9 vs. 91.3+-12.8 mm Hg (p&lt;0,01). The significant differencesof DCV was found among tertils (1.51+-1.11 vs 1.80+-1.04 vs. 1.99+-0.98 DCV, p&lt;0.01). Aortic PP together with age and hyperlipoproteinemia were found as factors with an independent relationship to DCV according to multivariate linear r

Název v anglickém jazyce

Relationship between high aortic pulse pressure and extension of coronary atherosclerosis in males

Popis výsledku anglicky

A high pulse pressure (PP) is a marker of increased artery stiffness and represents a well - established independent predictor for cardiovascular morbidity and mortality. The objective of the research was to determine whether invasively measured centralaortic PP was related to the presence and severity of coronary artery disease. In total 1075 consecutive stable male patients undergoing diagnostic coronary angiography with a preserved left ventricular function were included. Diseased coronary vessel (DCV) was defined by the presence of &gt; 50% stenosis. Results: Men were divided into 3 groups according to the increased value of PP. The average PP in the tertils was 47.8+-7.1 vs. 67.0+-4.9 vs. 91.3+-12.8 mm Hg (p&lt;0,01). The significant differencesof DCV was found among tertils (1.51+-1.11 vs 1.80+-1.04 vs. 1.99+-0.98 DCV, p&lt;0.01). Aortic PP together with age and hyperlipoproteinemia were found as factors with an independent relationship to DCV according to multivariate linear r

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FA - Kardiovaskulární nemoci včetně kardiochirurgie

OECD FORD obor

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Projekt

<a href="/cs/project/NR9356" target="_blank" >NR9356: Komplexní zhodnocení vlivu polymorfismu matrix metalloproteináz-1,2,3,9, tkáńového inhibitoru matrix metaloproteináz-1 a ACE na remodelaci levé komory a střednědobou prognózu po akutním infarktu mykardu s ST elevacemi léčeném primární PCI</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Physiological Researach

ISSN

0862-8408

e-ISSN

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Svazek periodika

60

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

47-53

Kód UT WoS článku

000288563800005

EID výsledku v databázi Scopus

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