The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F13%3A%230002086" target="_blank" >RIV/65269705:_____/13:#0002086 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1155/2013/908741" target="_blank" >http://dx.doi.org/10.1155/2013/908741</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/2013/908741" target="_blank" >10.1155/2013/908741</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients

Popis výsledku v původním jazyce

Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement. While the absence of neurological ?cerebellar signs? in most dystonia patients may be considered at least provoking, there are more subtle indications of cerebellar dysfunction in complex, demanding tasks. Specifically, given the role of the cerebellum in the neural representation oftime, in the millisecond range, dysfunction to this structure is considered to be of greater importance than dysfunction of the basal ganglia. In the current study,we investigated the performance of cervical dystonia patients on a computer task known toengage the cerebellum, namely, the interception of a moving target with changing parameters (speed, acceleration, and angle) with a simple response (pushing a button). The cervical dystonia patients achieved significantly worse results t

Název v anglickém jazyce

The Mechanisms of Movement Control and Time Estimation in Cervical Dystonia Patients

Popis výsledku anglicky

Traditionally, the pathophysiology of cervical dystonia has been regarded mainly in relation to neurochemical abnormities in the basal ganglia. Recently, however, substantial evidence has emerged for cerebellar involvement. While the absence of neurological ?cerebellar signs? in most dystonia patients may be considered at least provoking, there are more subtle indications of cerebellar dysfunction in complex, demanding tasks. Specifically, given the role of the cerebellum in the neural representation oftime, in the millisecond range, dysfunction to this structure is considered to be of greater importance than dysfunction of the basal ganglia. In the current study,we investigated the performance of cervical dystonia patients on a computer task known toengage the cerebellum, namely, the interception of a moving target with changing parameters (speed, acceleration, and angle) with a simple response (pushing a button). The cervical dystonia patients achieved significantly worse results t

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

<a href="/cs/project/NT13437" target="_blank" >NT13437: Mozeček, kognitivní dysfunkce a mechanismy kontroly pohybu a odhadu času u dystonie a schizofrenie.</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Neural Plasticity

ISSN

1687-5443

e-ISSN

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Svazek periodika

2013

Číslo periodika v rámci svazku

2013

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

"UNSP 908741"

Kód UT WoS článku

000325567500001

EID výsledku v databázi Scopus

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