Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F18%3A00068534" target="_blank" >RIV/65269705:_____/18:00068534 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/18:00102797

Výsledek na webu

<a href="https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.12371" target="_blank" >https://obgyn.onlinelibrary.wiley.com/doi/epdf/10.1002/ijgo.12371</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/ijgo.12371" target="_blank" >10.1002/ijgo.12371</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

Popis výsledku v původním jazyce

Objective: To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. Methods: In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. Results: Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P&gt;0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. Conclusion: CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.

Název v anglickém jazyce

Comparison of the Copenhagen Index versus ROMA for the preoperative assessment of women with ovarian tumors

Popis výsledku anglicky

Objective: To compare the Copenhagen Index (CPH-I) and the Risk of Ovarian Malignancy Algorithm (ROMA) in the differential diagnosis of ovarian tumors. Methods: In a retrospective study, data were reviewed from women with ovarian tumors who attended University Hospital Brno, Czech Republic, between July 2011 and June 2015. The women were classified into the benign tumor group or malignant tumor group (borderline and malignant tumors). Serum levels of CA125 and HE4 were extracted from medical records. The two tumor indices were calculated using relevant clinical data. Results: Among 267 included women, 110 had benign tumors, 42 had borderline ovarian tumors, and 115 had malignant tumors. The two indices showed similar discriminatory performance with no significant differences (P&gt;0.05). In the differentiation of benign tumors from all stages of borderline tumor and ovarian cancer, ROMA showed a sensitivity of 71% at a specificity of 88%, whereas CPH-I showed a sensitivity of 69% at a specificity of 85%. Conclusion: CPH-I is a potential tumor index that is independent of menopausal status. It might be applied as a simple alternative to ROMA in settings of basic medical care.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30214 - Obstetrics and gynaecology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International journal of gynecology &amp; obstetrics

ISSN

0020-7292

e-ISSN

—

Svazek periodika

140

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

6

Strana od-do

241-246

Kód UT WoS článku

000419300300018

EID výsledku v databázi Scopus

2-s2.0-85034731855