Surgical treatment and management of cutaneous squamous cell carcinoma in patients with dystrophic epidermolysis bullosa – a case report

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F21%3A00075870" target="_blank" >RIV/65269705:_____/21:00075870 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.prolekare.cz/en/journals/acta-chirurgiae-plasticae/2021-4-18/surgical-treatment-and-management-of-cutaneous-squamous-cell-carcinoma-in-patients-with-dystrophic-epidermolysis-bullosa-a-case-report-129285" target="_blank" >https://www.prolekare.cz/en/journals/acta-chirurgiae-plasticae/2021-4-18/surgical-treatment-and-management-of-cutaneous-squamous-cell-carcinoma-in-patients-with-dystrophic-epidermolysis-bullosa-a-case-report-129285</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.48095/ccachp2021196" target="_blank" >10.48095/ccachp2021196</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Surgical treatment and management of cutaneous squamous cell carcinoma in patients with dystrophic epidermolysis bullosa – a case report

Popis výsledku v původním jazyce

Epidermolysis bullosa (EB) is a rare inherited disease which is characterized by blisters on the skin and mucous membranes. Some forms of EB are associated with a risk of squamous cell carcinoma (SCC) development, which, unlike in the general population, is formed at a young age. SCC is the most common cause of death in patients with a dystrophic form. It is necessary to examine chronic and non-healing wounds for an increased risk of SCC. The basic treatment consists of surgical excision of the tumor site with a wide margin into healthy tissue. The surgical wound can be healed by secondary intention to prevent further trauma of the patient. The radicality of the excision is influenced by the location of the tumor. On the body, it is considerably limited by the surrounding tissue; on the limb, it is necessary to consider its amputation. In case of dissemination of the disease, it is important to approach patients individually and discuss other treatment options, including palliative care, within the national EB Center. The therapy is focused on pain treatment, remedial surgical dressings and psychological support with an emphasis on maintaining the quality of life.

Název v anglickém jazyce

Surgical treatment and management of cutaneous squamous cell carcinoma in patients with dystrophic epidermolysis bullosa – a case report

Popis výsledku anglicky

Epidermolysis bullosa (EB) is a rare inherited disease which is characterized by blisters on the skin and mucous membranes. Some forms of EB are associated with a risk of squamous cell carcinoma (SCC) development, which, unlike in the general population, is formed at a young age. SCC is the most common cause of death in patients with a dystrophic form. It is necessary to examine chronic and non-healing wounds for an increased risk of SCC. The basic treatment consists of surgical excision of the tumor site with a wide margin into healthy tissue. The surgical wound can be healed by secondary intention to prevent further trauma of the patient. The radicality of the excision is influenced by the location of the tumor. On the body, it is considerably limited by the surrounding tissue; on the limb, it is necessary to consider its amputation. In case of dissemination of the disease, it is important to approach patients individually and discuss other treatment options, including palliative care, within the national EB Center. The therapy is focused on pain treatment, remedial surgical dressings and psychological support with an emphasis on maintaining the quality of life.

Druh

J_SC - Článek v periodiku v databázi SCOPUS

CEP obor

—

OECD FORD obor

30212 - Surgery

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta chirurgiae plasticae

ISSN

0001-5423

e-ISSN

—

Svazek periodika

63

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

5

Strana od-do

196-200

Kód UT WoS článku

—

EID výsledku v databázi Scopus

2-s2.0-85123264946