Speed of heart rate changes during postural provocations in children and adolescents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00079927" target="_blank" >RIV/65269705:_____/24:00079927 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00136804

Výsledek na webu

<a href="https://www.nature.com/articles/s41598-024-62000-7" target="_blank" >https://www.nature.com/articles/s41598-024-62000-7</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-024-62000-7" target="_blank" >10.1038/s41598-024-62000-7</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Speed of heart rate changes during postural provocations in children and adolescents

Popis výsledku v původním jazyce

Heart rate is under constant autonomic influence but the development of the influence in children is not fully understood. Continuous electrocardiograms were obtained in 1045 healthy school-age children (550 females) during postural provocations with body position changes between supine, sitting, standing, supine, standing, sitting and supine (in this order), 10 min in each position with position changes within 20 s. Heart rate was measured in each position and speed of heart rate changes between positions were assessed by regressions of rates versus timing of individual cardiac cycles. Supine heart rate was gradually decreasing with age: 82.32 +- 9.92, 74.33 +- 9.79, 67.43 +- 9.45 beats per minute (bpm) in tertile age groups &lt; 11, 11-15, &gt; 15 years, respectively (p &lt; 0.0001), with no significant sex difference. Averaged speed of heart rate changes differed little between sexes and age groups but was significantly faster during rate deceleration than acceleration (e.g., supine LEFT RIGHT ARROW standing: 2.99 +- 1.02 vs. 2.57 +- 0.68 bpm/s, p &lt; 0.0001). The study suggests that in children, vagal heart rate control does not noticeably change between ages of approximately 6-19 years. The gradual resting heart rate decrease during childhood and adolescence is likely caused by lowering of cardiac sympathetic influence from sympathetic overdrive in small children to adult-like sympatho-vagal balance in older adolescents. (C) The Author(s) 2024.

Název v anglickém jazyce

Speed of heart rate changes during postural provocations in children and adolescents

Popis výsledku anglicky

Heart rate is under constant autonomic influence but the development of the influence in children is not fully understood. Continuous electrocardiograms were obtained in 1045 healthy school-age children (550 females) during postural provocations with body position changes between supine, sitting, standing, supine, standing, sitting and supine (in this order), 10 min in each position with position changes within 20 s. Heart rate was measured in each position and speed of heart rate changes between positions were assessed by regressions of rates versus timing of individual cardiac cycles. Supine heart rate was gradually decreasing with age: 82.32 +- 9.92, 74.33 +- 9.79, 67.43 +- 9.45 beats per minute (bpm) in tertile age groups &lt; 11, 11-15, &gt; 15 years, respectively (p &lt; 0.0001), with no significant sex difference. Averaged speed of heart rate changes differed little between sexes and age groups but was significantly faster during rate deceleration than acceleration (e.g., supine LEFT RIGHT ARROW standing: 2.99 +- 1.02 vs. 2.57 +- 0.68 bpm/s, p &lt; 0.0001). The study suggests that in children, vagal heart rate control does not noticeably change between ages of approximately 6-19 years. The gradual resting heart rate decrease during childhood and adolescence is likely caused by lowering of cardiac sympathetic influence from sympathetic overdrive in small children to adult-like sympatho-vagal balance in older adolescents. (C) The Author(s) 2024.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10700 - Other natural sciences

Projekt

<a href="/cs/project/NV19-02-00197" target="_blank" >NV19-02-00197: Hodnocení dynamiky srdeční repolarizace při autonomních provokačních testech u dětí a vývoje mezipohlavních rozdílů u dospívajících</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Scientific Reports

ISSN

2045-2322

e-ISSN

2045-2322

Svazek periodika

14

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

19

Strana od-do

11938

Kód UT WoS článku

001233422900051

EID výsledku v databázi Scopus

2-s2.0-85194219959