Intra-Individual Relationship between Heart Rate Variability and the Underlying Heart Rate in Children and Adolescents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F24%3A00079929" target="_blank" >RIV/65269705:_____/24:00079929 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/24:00136123

Výsledek na webu

<a href="https://www.mdpi.com/2077-0383/13/10/2897" target="_blank" >https://www.mdpi.com/2077-0383/13/10/2897</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcm13102897" target="_blank" >10.3390/jcm13102897</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Intra-Individual Relationship between Heart Rate Variability and the Underlying Heart Rate in Children and Adolescents

Popis výsledku v původním jazyce

Background/Objective: The relationship between heart rate and heart rate variability (HRV) indices has been repeatedly studied in adults but limited data are available on the relationship in paediatric populations. Methods: Continuous 12-lead electrocardiograms were recorded in 1016 healthy children and adolescents (534 females) aged 4 to 19 years during postural manoeuvres with rapid changes between 10-min positions of supine -&gt; sitting -&gt; standing -&gt; supine -&gt; standing -&gt; sitting -&gt; supine. In each position, the averaged RR interval was measured together with four HRV indices, namely the SDNN, RMSSD, quasi-normalised high-frequency components (qnHF), and the proportions of low- and high-frequency components (LF/HF). In each subject, the slope of the linear regression between the repeated HRV measurements and the corresponding RR interval averages was calculated. Results: The intra-subject regression slopes, including their confidence intervals, were related to the age and sex of the subjects. The SDNN/RR, RMSSD/RR, and qnHF/RR slopes were significantly steeper (p &lt; 0.001) and the (LF/HF)/RR slopes were significantly shallower (p &lt; 0.001) in younger children compared to older children and adolescents. Conclusions: The study suggests that sympathetic and vagal influences on heart rate are present in both younger and older children. With advancing age, the sympatho-vagal balance gradually develops and allows the vagal control to suppress the sympathetic drive towards higher heart rates seen in younger age children.

Název v anglickém jazyce

Intra-Individual Relationship between Heart Rate Variability and the Underlying Heart Rate in Children and Adolescents

Popis výsledku anglicky

Background/Objective: The relationship between heart rate and heart rate variability (HRV) indices has been repeatedly studied in adults but limited data are available on the relationship in paediatric populations. Methods: Continuous 12-lead electrocardiograms were recorded in 1016 healthy children and adolescents (534 females) aged 4 to 19 years during postural manoeuvres with rapid changes between 10-min positions of supine -&gt; sitting -&gt; standing -&gt; supine -&gt; standing -&gt; sitting -&gt; supine. In each position, the averaged RR interval was measured together with four HRV indices, namely the SDNN, RMSSD, quasi-normalised high-frequency components (qnHF), and the proportions of low- and high-frequency components (LF/HF). In each subject, the slope of the linear regression between the repeated HRV measurements and the corresponding RR interval averages was calculated. Results: The intra-subject regression slopes, including their confidence intervals, were related to the age and sex of the subjects. The SDNN/RR, RMSSD/RR, and qnHF/RR slopes were significantly steeper (p &lt; 0.001) and the (LF/HF)/RR slopes were significantly shallower (p &lt; 0.001) in younger children compared to older children and adolescents. Conclusions: The study suggests that sympathetic and vagal influences on heart rate are present in both younger and older children. With advancing age, the sympatho-vagal balance gradually develops and allows the vagal control to suppress the sympathetic drive towards higher heart rates seen in younger age children.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30218 - General and internal medicine

Projekt

<a href="/cs/project/NV19-02-00197" target="_blank" >NV19-02-00197: Hodnocení dynamiky srdeční repolarizace při autonomních provokačních testech u dětí a vývoje mezipohlavních rozdílů u dospívajících</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2024

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Clinical Medicine

ISSN

2077-0383

e-ISSN

2077-0383

Svazek periodika

13

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

18

Strana od-do

2897

Kód UT WoS článku

001233553900001

EID výsledku v databázi Scopus

2-s2.0-85194234044