Brain Functional Connectivity Asymmetry: Left Hemisphere Is More Modular

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985807%3A_____%2F22%3A00557325" target="_blank" >RIV/67985807:_____/22:00557325 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00023752:_____/22:43920840 RIV/00216208:11120/22:43923514 RIV/68407700:21230/22:00358937

Výsledek na webu

<a href="http://dx.doi.org/10.3390/sym14040833" target="_blank" >http://dx.doi.org/10.3390/sym14040833</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/sym14040833" target="_blank" >10.3390/sym14040833</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Brain Functional Connectivity Asymmetry: Left Hemisphere Is More Modular

Popis výsledku v původním jazyce

Graph-theoretical approaches are increasingly used to study the brain and may enhance our understanding of its asymmetries. In this paper, we hypothesize that the structure of the left hemisphere is, on average, more modular. To this end, we analyzed resting-state functional magnetic resonance imaging data of 90 healthy subjects. We computed functional connectivity by Pearson’s correlation coefficient, turned the matrix into an unweighted graph by keeping a certain percentage of the strongest connections, and quantified modularity separately for the subgraph formed by each hemisphere. Our results show that the left hemisphere is more modular. The result is consistent across a range of binarization thresholds, regardless of whether the two hemispheres are thresholded together or separately. This illustrates that graph-theoretical analysis can provide a robust characterization of lateralization of brain functional connectivity.

Název v anglickém jazyce

Brain Functional Connectivity Asymmetry: Left Hemisphere Is More Modular

Popis výsledku anglicky

Graph-theoretical approaches are increasingly used to study the brain and may enhance our understanding of its asymmetries. In this paper, we hypothesize that the structure of the left hemisphere is, on average, more modular. To this end, we analyzed resting-state functional magnetic resonance imaging data of 90 healthy subjects. We computed functional connectivity by Pearson’s correlation coefficient, turned the matrix into an unweighted graph by keeping a certain percentage of the strongest connections, and quantified modularity separately for the subgraph formed by each hemisphere. Our results show that the left hemisphere is more modular. The result is consistent across a range of binarization thresholds, regardless of whether the two hemispheres are thresholded together or separately. This illustrates that graph-theoretical analysis can provide a robust characterization of lateralization of brain functional connectivity.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Symmetry-Basel

ISSN

2073-8994

e-ISSN

2073-8994

Svazek periodika

14

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

11

Strana od-do

833

Kód UT WoS článku

000785289600001

EID výsledku v databázi Scopus

2-s2.0-85129309396