Assessment of the relative biological effectiveness of LVR-15 nuclear reactor neutron beam by a simple animal model.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F02%3A20020112" target="_blank" >RIV/67985823:_____/02:20020112 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Assessment of the relative biological effectiveness of LVR-15 nuclear reactor neutron beam by a simple animal model.

Popis výsledku v původním jazyce

The 1-week-old rats were subjected to a whole body irradiation either by epithermal neutron beam of the LVR-15 nuclear reactor (Řež near Prague, the flux density 8.8 x 108 n/cm2s-1, reactor power 9 MW, the calculated physical dose 16.1 cGy/min, irradiation time 2.5, 5 or 7 min) or a Cs137 gamma ray source (Cesioterax, Chirana, Prague, 0.5, 1.0, 1.5 or 2.0 Gy, 0.402 Gy per min). 8h after irradiation, the radiation damage was manifested by apoptotic condensation of chromatin and shrinkage of cells followed by formation of the apoptotic bodies. Their incidence was proportional to the degree of maturation of the brain and the radiation dose. The radiation damage was most pronounced in the external granular layer (EGL) of the cerebellum and the subependymallayer of the forebrain. The Relative Biological Effectiveness (RBE) of the whole reactor beam spectrum, as determined by the comparison of the number of lethally damaged cells induced by both the reactor and Cs137 sources of radiation, w

Název v anglickém jazyce

Assessment of the relative biological effectiveness of LVR-15 nuclear reactor neutron beam by a simple animal model.

Popis výsledku anglicky

The 1-week-old rats were subjected to a whole body irradiation either by epithermal neutron beam of the LVR-15 nuclear reactor (Řež near Prague, the flux density 8.8 x 108 n/cm2s-1, reactor power 9 MW, the calculated physical dose 16.1 cGy/min, irradiation time 2.5, 5 or 7 min) or a Cs137 gamma ray source (Cesioterax, Chirana, Prague, 0.5, 1.0, 1.5 or 2.0 Gy, 0.402 Gy per min). 8h after irradiation, the radiation damage was manifested by apoptotic condensation of chromatin and shrinkage of cells followed by formation of the apoptotic bodies. Their incidence was proportional to the degree of maturation of the brain and the radiation dose. The radiation damage was most pronounced in the external granular layer (EGL) of the cerebellum and the subependymallayer of the forebrain. The Relative Biological Effectiveness (RBE) of the whole reactor beam spectrum, as determined by the comparison of the number of lethally damaged cells induced by both the reactor and Cs137 sources of radiation, w

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BG - Jaderná, atomová a molekulová fyzika, urychlovače

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2002

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Universitatis Purkynianae. Studia Biologica 6

ISSN

1212-3137

e-ISSN

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Svazek periodika

78

Číslo periodika v rámci svazku

N/A

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

13

Strana od-do

5-19

Kód UT WoS článku

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EID výsledku v databázi Scopus

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