Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F19%3A00504500" target="_blank" >RIV/67985823:_____/19:00504500 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216275:25310/19:39915941

Výsledek na webu

<a href="https://doi.org/10.1002/jssc.201800910" target="_blank" >https://doi.org/10.1002/jssc.201800910</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jssc.201800910" target="_blank" >10.1002/jssc.201800910</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS

Popis výsledku v původním jazyce

Saiga horn extracts were analyzed with the goal of obtaining new information about compounds present in it. The purpose of this study is to find synthetic alternatives to Saiga horn extract, which is used in traditional Chinese medicine, by identifying potentially biologically active compounds in the extracts. Using high‐performance liquid chromatography coupled with high‐resolution mass spectrometry, we have been able to identify a series of short‐chain polyhydroxybutyrates in alcoholic extracts of Saiga horn. Optimized high‐performance liquid chromatography coupled with tandem mass spectrometry methods for analysis of short‐chain poly‐3‐hydroxybutyrates were developed and subsequently applied to investigate Saiga horn extract for the presence of these compounds, which might explain its biological actions, particularly for its antipyretic and procoagulant properties.

Název v anglickém jazyce

Identification of short-chain poly-3-hydroxybutyrates in Saiga horn extracts using LC-MS/MS

Popis výsledku anglicky

Saiga horn extracts were analyzed with the goal of obtaining new information about compounds present in it. The purpose of this study is to find synthetic alternatives to Saiga horn extract, which is used in traditional Chinese medicine, by identifying potentially biologically active compounds in the extracts. Using high‐performance liquid chromatography coupled with high‐resolution mass spectrometry, we have been able to identify a series of short‐chain polyhydroxybutyrates in alcoholic extracts of Saiga horn. Optimized high‐performance liquid chromatography coupled with tandem mass spectrometry methods for analysis of short‐chain poly‐3‐hydroxybutyrates were developed and subsequently applied to investigate Saiga horn extract for the presence of these compounds, which might explain its biological actions, particularly for its antipyretic and procoagulant properties.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA17-10832S" target="_blank" >GA17-10832S: Pokročilá instrumentace a metodika pro separaci, analýzu a charakterizaci (bio)molekul kapilárními elektromigračními metodami.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Separation Science

ISSN

1615-9306

e-ISSN

—

Svazek periodika

42

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

12

Strana od-do

797-808

Kód UT WoS článku

000459327100002

EID výsledku v databázi Scopus

2-s2.0-85060336752