The electron beam irradiation of collagen in the dry and gel states: The effect of the dose and water content from the primary to the quaternary levels

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985891%3A_____%2F23%3A00576121" target="_blank" >RIV/67985891:_____/23:00576121 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61389005:_____/23:00576121 RIV/68407700:21220/23:00369499 RIV/00027022:_____/23:N0000047 RIV/60461373:22310/23:43927680

Výsledek na webu

<a href="https://doi.org/10.1016/j.ijbiomac.2023.126898" target="_blank" >https://doi.org/10.1016/j.ijbiomac.2023.126898</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijbiomac.2023.126898" target="_blank" >10.1016/j.ijbiomac.2023.126898</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The electron beam irradiation of collagen in the dry and gel states: The effect of the dose and water content from the primary to the quaternary levels

Popis výsledku v původním jazyce

The aim of our study was to describe the impact of collagen in the gel and dry state to various doses of electron beam radiation (1, 10 and 25 kGy) which are using for food processing and sterilization. The changes in the chemical compositions (water, amino acids, lipids, glycosaminoglycans) were analyzed and the changes in the structure (triple-helix or β-sheet, the integrity of the collagen) were assessed. Subsequently, the impact of the applied doses on the mechanical properties, stability in the enzymatic environment, swelling and morphology were determined. The irradiated gels evinced enhanced degrees of cross-linking with only partial degradation. Nevertheless, an increase was observed in their stability manifested via a higher degree of resistance to the enzymatic environment, a reduction in swelling and, in terms of the mechanical behaviour, an approximation to the non-linear behavior of native tissues. In contrast, irradiation in the dry state exerted a somewhat negative impact on the observed properties and was manifested mainly via the scission of the collagen molecule and via a lower degree of stability in the aqueous and enzymatic environments. Neither the chemical composition nor the morphology was affected by irradiation.

Název v anglickém jazyce

The electron beam irradiation of collagen in the dry and gel states: The effect of the dose and water content from the primary to the quaternary levels

Popis výsledku anglicky

The aim of our study was to describe the impact of collagen in the gel and dry state to various doses of electron beam radiation (1, 10 and 25 kGy) which are using for food processing and sterilization. The changes in the chemical compositions (water, amino acids, lipids, glycosaminoglycans) were analyzed and the changes in the structure (triple-helix or β-sheet, the integrity of the collagen) were assessed. Subsequently, the impact of the applied doses on the mechanical properties, stability in the enzymatic environment, swelling and morphology were determined. The irradiated gels evinced enhanced degrees of cross-linking with only partial degradation. Nevertheless, an increase was observed in their stability manifested via a higher degree of resistance to the enzymatic environment, a reduction in swelling and, in terms of the mechanical behaviour, an approximation to the non-linear behavior of native tissues. In contrast, irradiation in the dry state exerted a somewhat negative impact on the observed properties and was manifested mainly via the scission of the collagen molecule and via a lower degree of stability in the aqueous and enzymatic environments. Neither the chemical composition nor the morphology was affected by irradiation.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/GA21-07851S" target="_blank" >GA21-07851S: Studium metod modifikace mechanických vlastností a struktury kolagenní hmoty</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Biological Macromolecules

ISSN

0141-8130

e-ISSN

1879-0003

Svazek periodika

253

Číslo periodika v rámci svazku

31 DEC

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

13

Strana od-do

126898

Kód UT WoS článku

001082302400001

EID výsledku v databázi Scopus

2-s2.0-85172387532