The electron beam irradiation of type I bovine collagen gels: Insights into radiation dose and water content impacts on the composition and the structural, rheological, thermal and mechanical properties

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985891%3A_____%2F25%3A00638123" target="_blank" >RIV/67985891:_____/25:00638123 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00027006:_____/25:10179212 RIV/60461373:22310/25:43932650 RIV/68407700:21220/25:00384874

Výsledek na webu

<a href="https://doi.org/10.1016/j.ijbiomac.2025.146099" target="_blank" >https://doi.org/10.1016/j.ijbiomac.2025.146099</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijbiomac.2025.146099" target="_blank" >10.1016/j.ijbiomac.2025.146099</a>

Jazyk výsledku

angličtina

Název v původním jazyce

The electron beam irradiation of type I bovine collagen gels: Insights into radiation dose and water content impacts on the composition and the structural, rheological, thermal and mechanical properties

Popis výsledku v původním jazyce

This study examined the impacts of electron beam irradiation (0.25, 0,5, 1, 10 and 25 kGy) on bovine collagen hydrogels at a concentration of 3 wt%. The impact of irradiation was verified via the analysis of the mechanical, thermal and rheological properties, changes in the composition and structure of the collagen, its stability in the enzymatic environment, and its swelling and morphology. Both the degradation and cross-linking of the collagen mass were demonstrated in relation to the radiation dose. Degradation was proven via a decrease in the content of the triple helical part of the collagen and transformation into other collagen structural states, and cross-linking was demonstrated by an increase in the network chain density with the radiation dose. When compared with the non-irradiated gels, no significant qualitative changes in the configuration or ordering over longer distances were evident following the application of the irradiation doses. The apparent elastic modulus, overall thermal stability and rheological characteristics in the oscillatory regime, and the storage and loss moduli of elasticity correlated positively with the radiation dose.

Název v anglickém jazyce

The electron beam irradiation of type I bovine collagen gels: Insights into radiation dose and water content impacts on the composition and the structural, rheological, thermal and mechanical properties

Popis výsledku anglicky

This study examined the impacts of electron beam irradiation (0.25, 0,5, 1, 10 and 25 kGy) on bovine collagen hydrogels at a concentration of 3 wt%. The impact of irradiation was verified via the analysis of the mechanical, thermal and rheological properties, changes in the composition and structure of the collagen, its stability in the enzymatic environment, and its swelling and morphology. Both the degradation and cross-linking of the collagen mass were demonstrated in relation to the radiation dose. Degradation was proven via a decrease in the content of the triple helical part of the collagen and transformation into other collagen structural states, and cross-linking was demonstrated by an increase in the network chain density with the radiation dose. When compared with the non-irradiated gels, no significant qualitative changes in the configuration or ordering over longer distances were evident following the application of the irradiation doses. The apparent elastic modulus, overall thermal stability and rheological characteristics in the oscillatory regime, and the storage and loss moduli of elasticity correlated positively with the radiation dose.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Biological Macromolecules

ISSN

0141-8130

e-ISSN

1879-0003

Svazek periodika

320

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

16

Strana od-do

146099

Kód UT WoS článku

001541343200005

EID výsledku v databázi Scopus

2-s2.0-105010872458