Spontaneous regression of malignant melanoma - is it based on the interplay between host immune system and melanoma antigens?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00480626" target="_blank" >RIV/67985904:_____/17:00480626 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/60460709:41210/17:74868 RIV/00064211:_____/17:W0000017

Výsledek na webu

<a href="http://dx.doi.org/10.1097/CAD.0000000000000526" target="_blank" >http://dx.doi.org/10.1097/CAD.0000000000000526</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/CAD.0000000000000526" target="_blank" >10.1097/CAD.0000000000000526</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Spontaneous regression of malignant melanoma - is it based on the interplay between host immune system and melanoma antigens?

Popis výsledku v původním jazyce

Malignant melanoma (MM) is the most aggressive and uneasily treatable form of skin cancer. Up to 90% of deaths because of skin tumours are estimated to be caused by this malignancy. Spontaneous regression is described as a partial or complete disappearance of cancer. It can be defined if the clinical and histological diagnosis of malignancy is verified and any therapeutic intervention potentially inducing mechanisms leading to regression has not been applied. Regression occurs more frequently in melanoma than in other types of tumours, it is reported to be six times higher than in other malignancies. Up to 50% of primary MM is reported to undergo spontaneous regression. However, spontaneous regression of the metastatic form of tumour is a rare phenomenon observed in only 0.23% of cases. The most frequently mentioned factors leading to spontaneous regression of MM are operative trauma, infection, vaccination (BCG and rabies vaccines) and immunological factors. Other well-documented circumstances associated with regression of metastatic MM include blood transfusion and various endocrine factors.

Název v anglickém jazyce

Spontaneous regression of malignant melanoma - is it based on the interplay between host immune system and melanoma antigens?

Popis výsledku anglicky

Malignant melanoma (MM) is the most aggressive and uneasily treatable form of skin cancer. Up to 90% of deaths because of skin tumours are estimated to be caused by this malignancy. Spontaneous regression is described as a partial or complete disappearance of cancer. It can be defined if the clinical and histological diagnosis of malignancy is verified and any therapeutic intervention potentially inducing mechanisms leading to regression has not been applied. Regression occurs more frequently in melanoma than in other types of tumours, it is reported to be six times higher than in other malignancies. Up to 50% of primary MM is reported to undergo spontaneous regression. However, spontaneous regression of the metastatic form of tumour is a rare phenomenon observed in only 0.23% of cases. The most frequently mentioned factors leading to spontaneous regression of MM are operative trauma, infection, vaccination (BCG and rabies vaccines) and immunological factors. Other well-documented circumstances associated with regression of metastatic MM include blood transfusion and various endocrine factors.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30102 - Immunology

Projekt

<a href="/cs/project/LO1609" target="_blank" >LO1609: Modely závažných lidských onemocnění: Traumatické poškození míchy, Huntingtonova choroba, melanom a neplodnost</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Anti-cancer Drugs

ISSN

0959-4973

e-ISSN

—

Svazek periodika

28

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

819-830

Kód UT WoS článku

000408162400001

EID výsledku v databázi Scopus

2-s2.0-85020696178