Ten millennia of hepatitis B virus evolution

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985912%3A_____%2F21%3A00546479" target="_blank" >RIV/67985912:_____/21:00546479 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.science.org/doi/10.1126/science.abi5658" target="_blank" >https://www.science.org/doi/10.1126/science.abi5658</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1126/science.abi5658" target="_blank" >10.1126/science.abi5658</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ten millennia of hepatitis B virus evolution

Popis výsledku v původním jazyce

Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic.

Název v anglickém jazyce

Ten millennia of hepatitis B virus evolution

Popis výsledku anglicky

Hepatitis B virus (HBV) has been infecting humans for millennia and remains a global health problem, but its past diversity and dispersal routes are largely unknown. We generated HBV genomic data from 137 Eurasians and Native Americans dated between ~10,500 and ~400 years ago. We date the most recent common ancestor of all HBV lineages to between ~20,000 and 12,000 years ago, with the virus present in European and South American hunter-gatherers during the early Holocene. After the European Neolithic transition, Mesolithic HBV strains were replaced by a lineage likely disseminated by early farmers that prevailed throughout western Eurasia for ~4000 years, declining around the end of the 2nd millennium BCE. The only remnant of this prehistoric HBV diversity is the rare genotype G, which appears to have reemerged during the HIV pandemic.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

60102 - Archaeology

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Science

ISSN

0036-8075

e-ISSN

1095-9203

Svazek periodika

374

Číslo periodika v rámci svazku

6564

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

7

Strana od-do

182-188

Kód UT WoS článku

000704920400041

EID výsledku v databázi Scopus

2-s2.0-85118031627