Electrochemical analysis of proteins important in cancer: Behavior of anterior gradient receptors, p53 protein and their complexes at charged surfaces
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F23%3A00572133" target="_blank" >RIV/68081707:_____/23:00572133 - isvavai.cz</a>
Výsledek na webu
<a href="https://www.sciencedirect.com/science/article/pii/S2451910323000625?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2451910323000625?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.coelec.2023.101269" target="_blank" >10.1016/j.coelec.2023.101269</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Electrochemical analysis of proteins important in cancer: Behavior of anterior gradient receptors, p53 protein and their complexes at charged surfaces
Popis výsledku v původním jazyce
Electrochemical methods are one of the most utilized approaches for newly developing strategies of cancer biomarker detection. However, electrochemical methods can be used in cancer research also as techniques applicable for fast preliminary tests of protein structural changes and for clarifying protein interactions with the interacting partners including DNA, proteins, and peptides. In this review, we present some examples of electrochemical approaches, which help to understand the role of cancer protein(s) in biological pathways. Data obtained with protein p53 and anterior gradient proteins using chronopotentiometric stripping analysis provide information about the structural dynamics of a given protein and its complexes. The knowledge about biomacromolecule behavior at the charged surfaces can be further utilized in other fields including molecular biology, proteomics, glycomics as well as in sensorics.
Název v anglickém jazyce
Electrochemical analysis of proteins important in cancer: Behavior of anterior gradient receptors, p53 protein and their complexes at charged surfaces
Popis výsledku anglicky
Electrochemical methods are one of the most utilized approaches for newly developing strategies of cancer biomarker detection. However, electrochemical methods can be used in cancer research also as techniques applicable for fast preliminary tests of protein structural changes and for clarifying protein interactions with the interacting partners including DNA, proteins, and peptides. In this review, we present some examples of electrochemical approaches, which help to understand the role of cancer protein(s) in biological pathways. Data obtained with protein p53 and anterior gradient proteins using chronopotentiometric stripping analysis provide information about the structural dynamics of a given protein and its complexes. The knowledge about biomacromolecule behavior at the charged surfaces can be further utilized in other fields including molecular biology, proteomics, glycomics as well as in sensorics.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Návaznosti výsledku
Projekt
<a href="/cs/project/GA22-26590S" target="_blank" >GA22-26590S: Nové nástroje pro výzkum a diagnostiku glykanů a glykoproteinů s využitím elektrochemické analýzy a chemické modifikace.</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2023
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Current Opinion in Electrochemistry
ISSN
2451-9103
e-ISSN
2451-9103
Svazek periodika
39
Číslo periodika v rámci svazku
JUN 2023
Stát vydavatele periodika
NL - Nizozemsko
Počet stran výsledku
8
Strana od-do
101269
Kód UT WoS článku
000975020400001
EID výsledku v databázi Scopus
2-s2.0-85151548483