Biophysical and electrochemical studies of protein-nucleic acid interactions

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F15%3A00446270" target="_blank" >RIV/68081707:_____/15:00446270 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14740/15:00081381

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00706-014-1405-4" target="_blank" >http://dx.doi.org/10.1007/s00706-014-1405-4</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00706-014-1405-4" target="_blank" >10.1007/s00706-014-1405-4</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Biophysical and electrochemical studies of protein-nucleic acid interactions

Popis výsledku v původním jazyce

This review is devoted to biophysical and electrochemical methods used for studying protein-nucleic acid (NA) interactions. The importance of NA structure and protein-NA recognition for essential cellular processes, such as replication or transcription,is discussed to provide background for description of a range of biophysical chemistry methods that are applied to study a wide scope of protein-DNA and protein-RNA complexes. These techniques employ different detection principles with specific advantages and limitations and are often combined as mutually complementary approaches to provide a complete description of the interactions. Electrochemical methods have proven to be of great utility in such studies because they provide sensitive measurements and can be combined with other approaches that facilitate the protein-NA interactions. Recent applications of electrochemical methods in studies of protein-NA interactions are discussed in detail.

Název v anglickém jazyce

Biophysical and electrochemical studies of protein-nucleic acid interactions

Popis výsledku anglicky

This review is devoted to biophysical and electrochemical methods used for studying protein-nucleic acid (NA) interactions. The importance of NA structure and protein-NA recognition for essential cellular processes, such as replication or transcription,is discussed to provide background for description of a range of biophysical chemistry methods that are applied to study a wide scope of protein-DNA and protein-RNA complexes. These techniques employ different detection principles with specific advantages and limitations and are often combined as mutually complementary approaches to provide a complete description of the interactions. Electrochemical methods have proven to be of great utility in such studies because they provide sensitive measurements and can be combined with other approaches that facilitate the protein-NA interactions. Recent applications of electrochemical methods in studies of protein-NA interactions are discussed in detail.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Monatshefte fur Chemie

ISSN

0026-9247

e-ISSN

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Svazek periodika

146

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

17

Strana od-do

723-739

Kód UT WoS článku

000353219700002

EID výsledku v databázi Scopus

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