Capillary electrophoresis as a sample separation step to mass spectrometry analysis: A primer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F23%3A00572002" target="_blank" >RIV/68081715:_____/23:00572002 - isvavai.cz</a>

Výsledek na webu

<a href="https://hdl.handle.net/11104/0342843" target="_blank" >https://hdl.handle.net/11104/0342843</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.trac.2023.117093" target="_blank" >10.1016/j.trac.2023.117093</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Capillary electrophoresis as a sample separation step to mass spectrometry analysis: A primer

Popis výsledku v původním jazyce

Capillary electrophoresis (CE) is a separation technique that offers high resolution, great sensitivity, and short processing times. Mass spectrometry (MS) accurately characterizes ionized species based on mass and fragmentation patterns that identify analytes by their mass to charge ratio. Powerful analytical systems are enabled by hyphenating CE with MS. Introducing a sample separated into individual zones minimizes ion suppression and significantly enhances the capacities of MS. This review article is intended as an introduction to scientists and professionals who are already familiar with electrophoresis and are interested in learning about the analytical potential of CE-MS systems. Working principles and basic instrumentation, including the CE-MS interfaces, are included as the robust and sensitive interfaces are crucial to the acceptance of CE-MS systems in the (bio)analytical practice. A discussion of recent reports on CE-MS systems provides an overview of the latest advances, and the conclusions speculate on future developments.

Název v anglickém jazyce

Capillary electrophoresis as a sample separation step to mass spectrometry analysis: A primer

Popis výsledku anglicky

Capillary electrophoresis (CE) is a separation technique that offers high resolution, great sensitivity, and short processing times. Mass spectrometry (MS) accurately characterizes ionized species based on mass and fragmentation patterns that identify analytes by their mass to charge ratio. Powerful analytical systems are enabled by hyphenating CE with MS. Introducing a sample separated into individual zones minimizes ion suppression and significantly enhances the capacities of MS. This review article is intended as an introduction to scientists and professionals who are already familiar with electrophoresis and are interested in learning about the analytical potential of CE-MS systems. Working principles and basic instrumentation, including the CE-MS interfaces, are included as the robust and sensitive interfaces are crucial to the acceptance of CE-MS systems in the (bio)analytical practice. A discussion of recent reports on CE-MS systems provides an overview of the latest advances, and the conclusions speculate on future developments.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

TrAC-Trends in Analytical Chemistry

ISSN

0165-9936

e-ISSN

1879-3142

Svazek periodika

164

Číslo periodika v rámci svazku

JUL

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

14

Strana od-do

117093

Kód UT WoS článku

001001800400001

EID výsledku v databázi Scopus

2-s2.0-85159558454