Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F17%3A00480609" target="_blank" >RIV/68081723:_____/17:00480609 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/17:PU124301

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ceramint.2017.05.177" target="_blank" >http://dx.doi.org/10.1016/j.ceramint.2017.05.177</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ceramint.2017.05.177" target="_blank" >10.1016/j.ceramint.2017.05.177</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration

Popis výsledku v původním jazyce

An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613 gm, which were connected through windows with an average diameter of 161 mu m. The compressive strength of the sintered foam reached an average value of 2 MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100 degrees C. The milling process was demonstrated and scaffold examples were successfully manufactured.

Název v anglickém jazyce

Subtractive manufacturing of customized hydroxyapatite scaffolds for bone regeneration

Popis výsledku anglicky

An approach to the preparation of customized hydroxyapatite scaffolds for bone regeneration based on subtractive manufacturing has been developed. The developed method is intended as a simple alternative to rapid prototyping based on additive manufacturing methods. The method for the preparation of customized scaffolds consists in computer numerical controlled (CNC) milling of porous hydroxyapatite foam. The machinable foam for customized scaffolds was prepared by direct foaming of a colloidal hydroxyapatite suspension and the foam structure was consolidated by the gelcasting method. The optimal foam after sintering reached a high porosity of 83.3% and the cellular-like structure contained spherical pores with an average diameter of 613 gm, which were connected through windows with an average diameter of 161 mu m. The compressive strength of the sintered foam reached an average value of 2 MPa. CNC milling was tested at different stages of the production cycle of the porous foam and after the reinforcing of the foam by impregnation. The best results were obtained by milling the foam presintered at 1100 degrees C. The milling process was demonstrated and scaffold examples were successfully manufactured.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20504 - Ceramics

Projekt

<a href="/cs/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ceramics International

ISSN

0272-8842

e-ISSN

—

Svazek periodika

43

Číslo periodika v rámci svazku

14

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

11265-11273

Kód UT WoS článku

000405158100084

EID výsledku v databázi Scopus

2-s2.0-85019730826