Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F18%3A00491306" target="_blank" >RIV/68081723:_____/18:00491306 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/18:PU128107

Výsledek na webu

<a href="http://dx.doi.org/10.1111/jace.15523" target="_blank" >http://dx.doi.org/10.1111/jace.15523</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jace.15523" target="_blank" >10.1111/jace.15523</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

Popis výsledku v původním jazyce

Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430m, and the most frequent interconnecting pore window size 150m, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured.

Název v anglickém jazyce

Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications

Popis výsledku anglicky

Machinable hydroxyapatite foams for subtractive manufacturing of customized bone scaffolds have been developed. The foams were prepared by direct foaming of water-based hydroxyapatite suspension with dissolved epoxy resin. The foams were consolidated by gelation of the epoxy-based suspension in air atmosphere. The effect of processing conditions on the foam structure was investigated. The foams had a cellular-like structure with interconnected pores. The sintered foam with 78% open porosity, the most frequent pore size 430m, and the most frequent interconnecting pore window size 150m, has been chosen as the foam with the optimal structure from the viewpoint of an application in bone regeneration. The compressive strength of this sintered foam reached 3.3MPa. The machinability of the optimal foam was investigated using computer numerical controlled (CNC) milling of a test pattern. The milling tests were carried out with the foam at different processing stages and after impregnation with paraffin wax. The best milling result was obtained for a dried foam impregnated with paraffin. The applicability of the whole processing chain was demonstrated and a customized scaffold was manufactured.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20504 - Ceramics

Projekt

<a href="/cs/project/NV17-31276A" target="_blank" >NV17-31276A: Všestranné preklinické zhodnocení laterální lumbální intervertebrální dézy hybridním biodegradabilním nanokompozitním porézním implantátem.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of the American Ceramic Society

ISSN

0002-7820

e-ISSN

—

Svazek periodika

101

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

11

Strana od-do

3317-3327

Kód UT WoS článku

000434278100010

EID výsledku v databázi Scopus

2-s2.0-85043510687