Invasive electrophysiology for circuit discovery and study of comorbid psychiatric disorders in patients with epilepsy: challenges, opportunities, and novel technologies

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F21%3A00544767" target="_blank" >RIV/68081731:_____/21:00544767 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26220/21:PU141429 RIV/68407700:21460/21:00351148 RIV/68407700:21730/21:00351148

Výsledek na webu

<a href="https://www.frontiersin.org/articles/10.3389/fnhum.2021.702605/full" target="_blank" >https://www.frontiersin.org/articles/10.3389/fnhum.2021.702605/full</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3389/fnhum.2021.702605" target="_blank" >10.3389/fnhum.2021.702605</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Invasive electrophysiology for circuit discovery and study of comorbid psychiatric disorders in patients with epilepsy: challenges, opportunities, and novel technologies

Popis výsledku v původním jazyce

Intracranial electroencephalographic (iEEG) recordings from patients with epilepsy provide distinct opportunities and novel data for the study of co-occurring psychiatric disorders. Comorbid psychiatric disorders are very common in drug-resistant epilepsy and their added complexity warrants careful consideration. In this review, we first discuss psychiatric comorbidities and symptoms in patients with epilepsy. We describe how epilepsy can potentially impact patient presentation and how these factors can be addressed in the experimental designs of studies focused on the electrophysiologic correlates of mood. Second, we review emerging technologies to integrate long-term iEEG recording with dense behavioral tracking in naturalistic environments. Third, we explore questions on how best to address the intersection between epilepsy and psychiatric comorbidities. Advances in ambulatory iEEG and long-term behavioral monitoring technologies will be instrumental in studying the intersection of seizures, epilepsy, psychiatric comorbidities, and their underlying circuitry.

Název v anglickém jazyce

Invasive electrophysiology for circuit discovery and study of comorbid psychiatric disorders in patients with epilepsy: challenges, opportunities, and novel technologies

Popis výsledku anglicky

Intracranial electroencephalographic (iEEG) recordings from patients with epilepsy provide distinct opportunities and novel data for the study of co-occurring psychiatric disorders. Comorbid psychiatric disorders are very common in drug-resistant epilepsy and their added complexity warrants careful consideration. In this review, we first discuss psychiatric comorbidities and symptoms in patients with epilepsy. We describe how epilepsy can potentially impact patient presentation and how these factors can be addressed in the experimental designs of studies focused on the electrophysiologic correlates of mood. Second, we review emerging technologies to integrate long-term iEEG recording with dense behavioral tracking in naturalistic environments. Third, we explore questions on how best to address the intersection between epilepsy and psychiatric comorbidities. Advances in ambulatory iEEG and long-term behavioral monitoring technologies will be instrumental in studying the intersection of seizures, epilepsy, psychiatric comorbidities, and their underlying circuitry.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Frontiers in Human Neuroscience

ISSN

1662-5161

e-ISSN

1662-5161

Svazek periodika

15

Číslo periodika v rámci svazku

26 July

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

17

Strana od-do

702605

Kód UT WoS článku

000682787600001

EID výsledku v databázi Scopus

2-s2.0-85112214308