Wild cyclic voles maintain high neutral and MHC diversity without strong evidence for parasite-mediated selection

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F14%3A00432240" target="_blank" >RIV/68081766:_____/14:00432240 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s10682-014-9709-8" target="_blank" >http://dx.doi.org/10.1007/s10682-014-9709-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10682-014-9709-8" target="_blank" >10.1007/s10682-014-9709-8</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Wild cyclic voles maintain high neutral and MHC diversity without strong evidence for parasite-mediated selection

Popis výsledku v původním jazyce

The major histocompatibility complex (MHC) is an important component of vertebrate immune defense involved with self/nonself recognition and disease susceptibility. The high variability of genes of the MHC is thought to arise from both parasite-mediatedand sexual selection. An outstanding question involves the degree to which balancing selection can oppose genetic drift to maintain high MHC diversity in the face of population bottlenecks. To address this question we examined genetic diversity and population structure at neutral (microsatellite) and MHC genes in montane voles [Microtus montanus (Peale, 1848)] subject to high amplitude population fluctuations, and compared these to measures of infection by common gastrointestinal parasites. We found high neutral and MHC allelic variability, indicating low impacts of genetic drift despite large fluctuations in population size. Greater MHC diversity did not predict lower parasite richness or infection by the two most common endoparasites

Název v anglickém jazyce

Wild cyclic voles maintain high neutral and MHC diversity without strong evidence for parasite-mediated selection

Popis výsledku anglicky

The major histocompatibility complex (MHC) is an important component of vertebrate immune defense involved with self/nonself recognition and disease susceptibility. The high variability of genes of the MHC is thought to arise from both parasite-mediatedand sexual selection. An outstanding question involves the degree to which balancing selection can oppose genetic drift to maintain high MHC diversity in the face of population bottlenecks. To address this question we examined genetic diversity and population structure at neutral (microsatellite) and MHC genes in montane voles [Microtus montanus (Peale, 1848)] subject to high amplitude population fluctuations, and compared these to measures of infection by common gastrointestinal parasites. We found high neutral and MHC allelic variability, indicating low impacts of genetic drift despite large fluctuations in population size. Greater MHC diversity did not predict lower parasite richness or infection by the two most common endoparasites

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

EG - Zoologie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Evolutionary Ecology

ISSN

0269-7653

e-ISSN

—

Svazek periodika

28

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

19

Strana od-do

957-975

Kód UT WoS článku

000340496000010

EID výsledku v databázi Scopus

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