Nanofibers as Scaffolds for Cell Transfer in Tissue Regeneration

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F15%3A00459258" target="_blank" >RIV/68378041:_____/15:00459258 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Nanofibers as Scaffolds for Cell Transfer in Tissue Regeneration

Popis výsledku v původním jazyce

Nanofibrous materials that mimic the native extracellular matrix and promote the adhesion of various cells are being developed as tissue engineered scaffolds for the skin, bone, vasculature, heart, cornea, nervous system, and other tissues. As a new approach, nanofibers prepared from gelatin, PA6/12, PAN, PCL, PLA and PUR using industrial scale needleless technology have been introduced as potential cell carriers and evaluated in vitro using human mesenchymal stem cells (hMSC) and mouse limbal stem cells (mLSC). A viability assay as well as immunocytochemical examination revealed that hMSC as well as mLSC adhered, grew and proliferated on all tested nanofibers. This study confirmed that examined nanofibers have a promising potential for biomedical applications such as scaffolds for cell transfer in tissue regeneration.

Název v anglickém jazyce

Nanofibers as Scaffolds for Cell Transfer in Tissue Regeneration

Popis výsledku anglicky

Nanofibrous materials that mimic the native extracellular matrix and promote the adhesion of various cells are being developed as tissue engineered scaffolds for the skin, bone, vasculature, heart, cornea, nervous system, and other tissues. As a new approach, nanofibers prepared from gelatin, PA6/12, PAN, PCL, PLA and PUR using industrial scale needleless technology have been introduced as potential cell carriers and evaluated in vitro using human mesenchymal stem cells (hMSC) and mouse limbal stem cells (mLSC). A viability assay as well as immunocytochemical examination revealed that hMSC as well as mLSC adhered, grew and proliferated on all tested nanofibers. This study confirmed that examined nanofibers have a promising potential for biomedical applications such as scaffolds for cell transfer in tissue regeneration.

Druh

C - Kapitola v odborné knize

CEP obor

FP - Ostatní lékařské obory

OECD FORD obor

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Projekt

<a href="/cs/project/LO1309" target="_blank" >LO1309: Buněčná terapie a tkáňové náhrady</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

From Functionalized Nanostructures Towards Engineered Macrostructures

ISBN

978-80-88113-20-1

Počet stran výsledku

17

Strana od-do

82-98

Počet stran knihy

176

Název nakladatele

Epika

Místo vydání

Jindřichův Hradec

Kód UT WoS kapitoly

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