Ultrafine and Fine Particles and Hospital Admissions in Central Europe Results from the UFIREG Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F16%3A00472918" target="_blank" >RIV/68378041:_____/16:00472918 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1164/rccm.201510-2042OC" target="_blank" >http://dx.doi.org/10.1164/rccm.201510-2042OC</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1164/rccm.201510-2042OC" target="_blank" >10.1164/rccm.201510-2042OC</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ultrafine and Fine Particles and Hospital Admissions in Central Europe Results from the UFIREG Study

Popis výsledku v původním jazyce

Rationale:Evidence of short-term effects of ultrafine particles (UFP)on health is still inconsistent and few multicenter studies have been conducted so far especially in Europe. nnObjectives: Within the UFIREG project, we investigated the short-term effects of UFP and fine particulate matter (particulate matter with an aerodynamic diameter less than 2.5 mu m [PM2.5]) on daily cause-specific hospital admissions in five Central and Eastern European cities using harmonized protocols for measurements and analyses. nnMethods: Daily counts of cause-specific hospital admissions focusing on cardiovascular and respiratory diseases were obtained for Augsburg and Dresden (Germany), 2011-2012; Chernivtsi (Ukraine), 2013 to March 2014; and Ljubljana (Slovenia) and Prague (Czech Republic), 2012-2013. Air pollution and meteorologic data were measured at fixed monitoring sites in all cities. We analyzed city-specific associations using confounder-adjusted Poisson regression models and pooled the city-specific effect estimates using metaanalysis methods. nnMeasurements and Main Results: A 2,750 particles/cm(3) increase (average interquartile range across all cities) in the 6-day average of UFP indicated a delayed and prolonged increase in the pooled relative risk of respiratory hospital admissions (3.4% [95% confidence interval,-1.7 to 8.8%]). We also found increases in the pooled relative risk of cardiovascular (exposure average of lag 2-5, 1.8% [0.1-3.4%) and respiratory (6-d average exposure, 7.5% [4.9-10.2%]) admissions per 12.4 mu g/m(3) increase (average interquartile range) in PM2.5. nnConclusions: Our findings indicated delayed and prolonged effects of UFP exposure on respiratory hospital admissions in Central and Eastern Europe. Cardiovascular and respiratory hospital admissions increased in association with an increase in PM2.5. Further multicenter studies are needed using harmonized UFP measurements to draw definite conclusions on health effects of UFP.

Název v anglickém jazyce

Ultrafine and Fine Particles and Hospital Admissions in Central Europe Results from the UFIREG Study

Popis výsledku anglicky

Rationale:Evidence of short-term effects of ultrafine particles (UFP)on health is still inconsistent and few multicenter studies have been conducted so far especially in Europe. nnObjectives: Within the UFIREG project, we investigated the short-term effects of UFP and fine particulate matter (particulate matter with an aerodynamic diameter less than 2.5 mu m [PM2.5]) on daily cause-specific hospital admissions in five Central and Eastern European cities using harmonized protocols for measurements and analyses. nnMethods: Daily counts of cause-specific hospital admissions focusing on cardiovascular and respiratory diseases were obtained for Augsburg and Dresden (Germany), 2011-2012; Chernivtsi (Ukraine), 2013 to March 2014; and Ljubljana (Slovenia) and Prague (Czech Republic), 2012-2013. Air pollution and meteorologic data were measured at fixed monitoring sites in all cities. We analyzed city-specific associations using confounder-adjusted Poisson regression models and pooled the city-specific effect estimates using metaanalysis methods. nnMeasurements and Main Results: A 2,750 particles/cm(3) increase (average interquartile range across all cities) in the 6-day average of UFP indicated a delayed and prolonged increase in the pooled relative risk of respiratory hospital admissions (3.4% [95% confidence interval,-1.7 to 8.8%]). We also found increases in the pooled relative risk of cardiovascular (exposure average of lag 2-5, 1.8% [0.1-3.4%) and respiratory (6-d average exposure, 7.5% [4.9-10.2%]) admissions per 12.4 mu g/m(3) increase (average interquartile range) in PM2.5. nnConclusions: Our findings indicated delayed and prolonged effects of UFP exposure on respiratory hospital admissions in Central and Eastern Europe. Cardiovascular and respiratory hospital admissions increased in association with an increase in PM2.5. Further multicenter studies are needed using harmonized UFP measurements to draw definite conclusions on health effects of UFP.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

DN - Vliv životního prostředí na zdraví

OECD FORD obor

—

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

American Journal of Respiratory and Critical Care Medicine

ISSN

1073-449X

e-ISSN

—

Svazek periodika

194

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

1233-1241

Kód UT WoS článku

000388250800012

EID výsledku v databázi Scopus

2-s2.0-84998962671