Composite Hydrogel Scaffolds for the Regeneration of Osteochondral Defects

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F16%3A00476178" target="_blank" >RIV/68378041:_____/16:00476178 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Composite Hydrogel Scaffolds for the Regeneration of Osteochondral Defects

Popis výsledku v původním jazyce

Even in 1982, Benya and Shaffer reported re-expression of chondrogenic phenotype of dedifferentiated chondrocytes after their embedding intro three-dimensional agarose hydrogel. From that time many different hydrogel scaffolds were studied in vitro and in vivo. Hydrogels provide a proper environment for cell growth and differentiation . However, they have several limitations, e.g. low mechanical properties or fast degradation, which leads to development of synthetic hydrogels and/or composite scaffolds. Composite scaffolds can be prepared as blend hydrogels, but often hydrogel form a separate chondral part of multi-layered scaffolds.

Název v anglickém jazyce

Composite Hydrogel Scaffolds for the Regeneration of Osteochondral Defects

Popis výsledku anglicky

Even in 1982, Benya and Shaffer reported re-expression of chondrogenic phenotype of dedifferentiated chondrocytes after their embedding intro three-dimensional agarose hydrogel. From that time many different hydrogel scaffolds were studied in vitro and in vivo. Hydrogels provide a proper environment for cell growth and differentiation . However, they have several limitations, e.g. low mechanical properties or fast degradation, which leads to development of synthetic hydrogels and/or composite scaffolds. Composite scaffolds can be prepared as blend hydrogels, but often hydrogel form a separate chondral part of multi-layered scaffolds.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)

Projekt

<a href="/cs/project/LO1309" target="_blank" >LO1309: Buněčná terapie a tkáňové náhrady</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Novel Biomaterials in Regenerative Medicine

ISBN

978-80-88113-69-0

Počet stran výsledku

11

Strana od-do

188-198

Počet stran knihy

276

Název nakladatele

Epika

Místo vydání

2016

Kód UT WoS kapitoly

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