The role of mesenchymal stromal cells in spinal cord injury

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00472194" target="_blank" >RIV/68378041:_____/17:00472194 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The role of mesenchymal stromal cells in spinal cord injury

Popis výsledku v původním jazyce

Spinal cord injury (SCI) is one of the most devastating diseases that affects patients and their families for the rest of their lives. Among many treatments being developed for SCI, the placement of different types of grafts embedded with cell populations into areas of damage has been one of the most commonly usednregenerative approaches ,attracting scientists and physicians for the last 15 years. Stem/stromal cells are able to secrete a large repertoire of signaling molecules, including anti-inflammatory cytokines and growth factors, which may modulate the inhibitory environment of SCI while increasing trophic support to the resident cells. The chapter describes the pathology of spinal cord injury, the use of mesenchymal stromal cells derived from different sources in the treatment of SCI and their potential modifications and manipulations to reinforce their paracrine effect on neural tissue regeneration. n

Název v anglickém jazyce

The role of mesenchymal stromal cells in spinal cord injury

Popis výsledku anglicky

Spinal cord injury (SCI) is one of the most devastating diseases that affects patients and their families for the rest of their lives. Among many treatments being developed for SCI, the placement of different types of grafts embedded with cell populations into areas of damage has been one of the most commonly usednregenerative approaches ,attracting scientists and physicians for the last 15 years. Stem/stromal cells are able to secrete a large repertoire of signaling molecules, including anti-inflammatory cytokines and growth factors, which may modulate the inhibitory environment of SCI while increasing trophic support to the resident cells. The chapter describes the pathology of spinal cord injury, the use of mesenchymal stromal cells derived from different sources in the treatment of SCI and their potential modifications and manipulations to reinforce their paracrine effect on neural tissue regeneration. n

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

<a href="/cs/project/LO1309" target="_blank" >LO1309: Buněčná terapie a tkáňové náhrady</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

The Biology and Therapeutic Applications of Mesenchymal Cells

ISBN

978-1-118-90751-1

Počet stran výsledku

16

Strana od-do

714-729

Počet stran knihy

1048

Název nakladatele

Wiley-Blackwell

Místo vydání

Oxford

Kód UT WoS kapitoly

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