Designing of PLA scaffolds for bone tissue replacement fabricated by ordinary commercial 3D printer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00481441" target="_blank" >RIV/68378041:_____/17:00481441 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11110/17:10369802 RIV/00216208:11310/17:10369802 RIV/00216208:11130/17:10369802 RIV/62157124:16170/17:43875782 a 3 dalších

Výsledek na webu

<a href="http://dx.doi.org/10.1186/s13036-017-0074-3" target="_blank" >http://dx.doi.org/10.1186/s13036-017-0074-3</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1186/s13036-017-0074-3" target="_blank" >10.1186/s13036-017-0074-3</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Designing of PLA scaffolds for bone tissue replacement fabricated by ordinary commercial 3D printer

Popis výsledku v původním jazyce

In tissue engineering, scaffolds are used for cell culture. Biodegradable scaffolds gradually degrade and are replaced by new formed tissue. Automatic manufacturing, e.g. by Rapid Prototyping, enables to prepare scaffolds of precise structure, shape and size. In the work we have tested commercially available 3D printer and polylactic acid was used as a tested material. Structures with different geometry have been prepared and tested with osteosarcomas cells. Moreover, biomechanical properties of the scaffolds have been tested. Porosity lower than 90% did not affect cell proliferation, and scaffolds demonstrated better biomechanical properties. Our work showed possibilities and limitations during the scaffolds preparation using Rapid Prototyping.

Název v anglickém jazyce

Designing of PLA scaffolds for bone tissue replacement fabricated by ordinary commercial 3D printer

Popis výsledku anglicky

In tissue engineering, scaffolds are used for cell culture. Biodegradable scaffolds gradually degrade and are replaced by new formed tissue. Automatic manufacturing, e.g. by Rapid Prototyping, enables to prepare scaffolds of precise structure, shape and size. In the work we have tested commercially available 3D printer and polylactic acid was used as a tested material. Structures with different geometry have been prepared and tested with osteosarcomas cells. Moreover, biomechanical properties of the scaffolds have been tested. Porosity lower than 90% did not affect cell proliferation, and scaffolds demonstrated better biomechanical properties. Our work showed possibilities and limitations during the scaffolds preparation using Rapid Prototyping.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Biological Engineering

ISSN

1754-1611

e-ISSN

—

Svazek periodika

11

Číslo periodika v rámci svazku

oct

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

21

Strana od-do

—

Kód UT WoS článku

000412909300001

EID výsledku v databázi Scopus

2-s2.0-85031413991