Mesenchymal Stem Cells and Their Trans-differentiation in Repair of Specific Tissues

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00491292" target="_blank" >RIV/68378041:_____/17:00491292 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Mesenchymal Stem Cells and Their Trans-differentiation in Repair of Specific Tissues

Popis výsledku v původním jazyce

Mesenchymal stem cells (MSCs) naturally differentiate into cells of tissues of mesodermal lineage: cartilage, bone or adipose tissue. As a result of specific environmental stimuli, MSC are able to transdifferentiate into cells of endodermal or ectodermal lineage. Also, MSCs are able to regulate the inflammatory processes and to support healing and regeneration. These properties make MSCs suitable in cell-based therapy and tissue engineering. Characteristics of MSCs (for example differentiation and proliferative potential and cytokine secretion profile) can vary depending on their origin. Moreover, these differences can be further amplified by the effects of specific environments. Thus, to obtain maximal therapeutic benefit, it is important to select the proper type of MSCs optimal for a particular environment.

Název v anglickém jazyce

Mesenchymal Stem Cells and Their Trans-differentiation in Repair of Specific Tissues

Popis výsledku anglicky

Mesenchymal stem cells (MSCs) naturally differentiate into cells of tissues of mesodermal lineage: cartilage, bone or adipose tissue. As a result of specific environmental stimuli, MSC are able to transdifferentiate into cells of endodermal or ectodermal lineage. Also, MSCs are able to regulate the inflammatory processes and to support healing and regeneration. These properties make MSCs suitable in cell-based therapy and tissue engineering. Characteristics of MSCs (for example differentiation and proliferative potential and cytokine secretion profile) can vary depending on their origin. Moreover, these differences can be further amplified by the effects of specific environments. Thus, to obtain maximal therapeutic benefit, it is important to select the proper type of MSCs optimal for a particular environment.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10601 - Cell biology

Projekt

<a href="/cs/project/LO1309" target="_blank" >LO1309: Buněčná terapie a tkáňové náhrady</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Nanomaterials in Biomedical research

ISBN

978-80-906655-5-2

Počet stran výsledku

7

Strana od-do

61-67

Počet stran knihy

140

Název nakladatele

Proxima Tisk, s.r.o.

Místo vydání

Praha 3

Kód UT WoS kapitoly

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