Dynamic creep properties of a novel nanofiber hernia mesh in abdominal wall repair

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F19%3A00518443" target="_blank" >RIV/68378041:_____/19:00518443 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21460/19:00338926 RIV/00216208:11510/19:10400250 RIV/00064203:_____/19:10400250 RIV/00216208:11130/19:10400250

Výsledek na webu

<a href="https://link.springer.com/article/10.1007%2Fs10029-019-01940-w" target="_blank" >https://link.springer.com/article/10.1007%2Fs10029-019-01940-w</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s10029-019-01940-w" target="_blank" >10.1007/s10029-019-01940-w</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Dynamic creep properties of a novel nanofiber hernia mesh in abdominal wall repair

Popis výsledku v původním jazyce

PurposeIncisional hernia is the most common complication following abdominal surgery. While mesh repair is common, none of the current meshes mimic the physiology of the abdominal wall. This study compares suture only repair with polypropylene mesh and a prototype of a novel implant (poly-epsilon-caprolactone nanofibers) and their influence on the physiology of an abdominal wall in an animal model.Methods27 Chinchilla rabbits were divided into six groups based on the type of the implant. Midline abdominal incision was repaired using one of the compared materials with suture alone serving as the control. 6 weeks post-surgery animals were killed and their explanted abdominal wall subjected to biomechanical testing.ResultsBoth-hysteresis and maximum strength curves showed high elasticity and strength in groups where the novel implant was used. Polypropylene mesh proved as stiff and fragile compared to other groups.ConclusionPoly-epsilon-caprolactone nanofiber scaffold is able to improve the dynamic properties of healing fascia with no loss of maximum tensile strength when compared to polypropylene mesh in an animal model.

Název v anglickém jazyce

Dynamic creep properties of a novel nanofiber hernia mesh in abdominal wall repair

Popis výsledku anglicky

PurposeIncisional hernia is the most common complication following abdominal surgery. While mesh repair is common, none of the current meshes mimic the physiology of the abdominal wall. This study compares suture only repair with polypropylene mesh and a prototype of a novel implant (poly-epsilon-caprolactone nanofibers) and their influence on the physiology of an abdominal wall in an animal model.Methods27 Chinchilla rabbits were divided into six groups based on the type of the implant. Midline abdominal incision was repaired using one of the compared materials with suture alone serving as the control. 6 weeks post-surgery animals were killed and their explanted abdominal wall subjected to biomechanical testing.ResultsBoth-hysteresis and maximum strength curves showed high elasticity and strength in groups where the novel implant was used. Polypropylene mesh proved as stiff and fragile compared to other groups.ConclusionPoly-epsilon-caprolactone nanofiber scaffold is able to improve the dynamic properties of healing fascia with no loss of maximum tensile strength when compared to polypropylene mesh in an animal model.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10610 - Biophysics

Projekt

<a href="/cs/project/NV17-32285A" target="_blank" >NV17-32285A: Funkcionalizovaná nanovlákna v prevenci vzniku kýly v jizvě</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Hernia

ISSN

1265-4906

e-ISSN

—

Svazek periodika

23

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

7

Strana od-do

1009-1015

Kód UT WoS článku

000495397400020

EID výsledku v databázi Scopus

2-s2.0-85064496355