30 years with avian leukosis virus subgroup J. Can we get rid of it via biotechnology?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523224" target="_blank" >RIV/68378050:_____/19:00523224 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

30 years with avian leukosis virus subgroup J. Can we get rid of it via biotechnology?

Popis výsledku v původním jazyce

Avian leukosis virus subgroup J (and quite recently also subgroup K) display all hallmarks of newly emerging infection, i.e. sudden appearance (via recombinantion of exogenous and endogenous retroviruses), rapid spread, and evolution. Although currently eradicated in Europe and USA, ALV-J is a scourge for the poultry industry in Asia and the risk of long-distance spread of the Asian variants still exists. Herein, the parallel of avian leukosis virus subgroup J and highly pathogenic avian influenza virus is used for explaining the peril of new outbreaks of viruses. In a long-term effort, our laboratory identified critical amino-acids of the Na+/H+ exchanger type 1, the receptor for avain leukosis virus subgroup J, which are necessary for virus binding and cell entry. This opens a way for biotechnological solution and creation of artificially resistant chickens.

Název v anglickém jazyce

30 years with avian leukosis virus subgroup J. Can we get rid of it via biotechnology?

Popis výsledku anglicky

Avian leukosis virus subgroup J (and quite recently also subgroup K) display all hallmarks of newly emerging infection, i.e. sudden appearance (via recombinantion of exogenous and endogenous retroviruses), rapid spread, and evolution. Although currently eradicated in Europe and USA, ALV-J is a scourge for the poultry industry in Asia and the risk of long-distance spread of the Asian variants still exists. Herein, the parallel of avian leukosis virus subgroup J and highly pathogenic avian influenza virus is used for explaining the peril of new outbreaks of viruses. In a long-term effort, our laboratory identified critical amino-acids of the Na+/H+ exchanger type 1, the receptor for avain leukosis virus subgroup J, which are necessary for virus binding and cell entry. This opens a way for biotechnological solution and creation of artificially resistant chickens.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10607 - Virology

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Advances in Disease Models

ISBN

978-80-88011-06-4

Počet stran výsledku

10

Strana od-do

82-91

Počet stran knihy

310

Název nakladatele

OPTIO CZ

Místo vydání

Praha

Kód UT WoS kapitoly

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