Introduction to RNAi and miRNA pathways

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F19%3A00523483" target="_blank" >RIV/68378050:_____/19:00523483 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Introduction to RNAi and miRNA pathways

Popis výsledku v původním jazyce

RNA silencing denotes a group of pathways, which utilize small RNAs as sequence-specific guides for repressing gene expression. Two related RNA silencing pathways exist in animals and plants: RNA interference (RNAi) and microRNA (miRNA) pathway. While the miRNA pathway serves to regulate endogenous protein-coding gene expression, RNAi serves as a form of innate immunity targeting viruses and mobile elements, although it occasionally also acquired function in protein-coding gene regulation. The aim of the following text is to provide an elementary introduction into RNAi and miRNA pathways for a series of taxon-specific and feature-specific reviews, which follow. The idea is to bring up common general principles allowing the reader to better navigate through common and derived mechanisms and functions of RNA silencing presented taxon-oriented review. The whole review series has been derived from a material for an expert report for the European Food and Safety Agency, which I wished to reorganize and make more accessible to the scientific community.

Název v anglickém jazyce

Introduction to RNAi and miRNA pathways

Popis výsledku anglicky

RNA silencing denotes a group of pathways, which utilize small RNAs as sequence-specific guides for repressing gene expression. Two related RNA silencing pathways exist in animals and plants: RNA interference (RNAi) and microRNA (miRNA) pathway. While the miRNA pathway serves to regulate endogenous protein-coding gene expression, RNAi serves as a form of innate immunity targeting viruses and mobile elements, although it occasionally also acquired function in protein-coding gene regulation. The aim of the following text is to provide an elementary introduction into RNAi and miRNA pathways for a series of taxon-specific and feature-specific reviews, which follow. The idea is to bring up common general principles allowing the reader to better navigate through common and derived mechanisms and functions of RNA silencing presented taxon-oriented review. The whole review series has been derived from a material for an expert report for the European Food and Safety Agency, which I wished to reorganize and make more accessible to the scientific community.

Druh

C - Kapitola v odborné knize

CEP obor

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OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/LO1220" target="_blank" >LO1220: CZ-OPENSCREEN: Národní infrastruktura chemické biologie</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název knihy nebo sborníku

Introduction to RNAi and miRNA pathways

ISBN

978-80-246-4372-4

Počet stran výsledku

24

Strana od-do

1-339

Počet stran knihy

339

Název nakladatele

Karolinum

Místo vydání

Praha

Kód UT WoS kapitoly

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