Ultra-performance chromatographic methods for enantioseparation of liquid crystals based on lactic acid

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F19%3A00511147" target="_blank" >RIV/68378271:_____/19:00511147 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11310/19:10393976

Výsledek na webu

<a href="https://doi.org/10.1016/j.supflu.2019.02.002" target="_blank" >https://doi.org/10.1016/j.supflu.2019.02.002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.supflu.2019.02.002" target="_blank" >10.1016/j.supflu.2019.02.002</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Ultra-performance chromatographic methods for enantioseparation of liquid crystals based on lactic acid

Popis výsledku v původním jazyce

Fast and efficient ultra-performance chromatographic methods were developed for enantioseparation of new liquid crystals based on lactic acid. Ultra-performance supercritical fluid chromatography and non-aqueous reversed-phase liquid chromatography were applied for the first time for enantioseparation of this type of analytes. Both techniques proved to be suitable and baseline enantioseparation of all compounds was achieved with tris(3,5-dimethylphenylcarbamate) derivative of amylose as chiral selector. The compounds differentiate in number of benzene rings, length of alkyl side chains and presence of chlorine as lateral substituent and the effect of analyte structure on the enantioseparation was assessed. Significant effect of type of mobile phase modifier was observed in both systems including switching the enantiomer elution order based on both the type of the modifier (both techniques) and its portion in mobile phase (non-aqueous reversed-phase mode only).

Název v anglickém jazyce

Ultra-performance chromatographic methods for enantioseparation of liquid crystals based on lactic acid

Popis výsledku anglicky

Fast and efficient ultra-performance chromatographic methods were developed for enantioseparation of new liquid crystals based on lactic acid. Ultra-performance supercritical fluid chromatography and non-aqueous reversed-phase liquid chromatography were applied for the first time for enantioseparation of this type of analytes. Both techniques proved to be suitable and baseline enantioseparation of all compounds was achieved with tris(3,5-dimethylphenylcarbamate) derivative of amylose as chiral selector. The compounds differentiate in number of benzene rings, length of alkyl side chains and presence of chlorine as lateral substituent and the effect of analyte structure on the enantioseparation was assessed. Significant effect of type of mobile phase modifier was observed in both systems including switching the enantiomer elution order based on both the type of the modifier (both techniques) and its portion in mobile phase (non-aqueous reversed-phase mode only).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10406 - Analytical chemistry

Projekt

<a href="/cs/project/GA18-14497S" target="_blank" >GA18-14497S: Funkční organické-anorganické nanostruktury vykazující samouspořádání</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Supercritical Fluids

ISSN

0896-8446

e-ISSN

—

Svazek periodika

146

Číslo periodika v rámci svazku

Apr

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

9

Strana od-do

217-225

Kód UT WoS článku

000461402600025

EID výsledku v databázi Scopus

2-s2.0-85061425613